Your browser doesn't support javascript.
COVID-19 vaccination significantly reduces morbidity and absenteeism among healthcare personnel: A prospective multicenter study.
Maltezou, Helena C; Panagopoulos, Periklis; Sourri, Flora; Giannouchos, Theodoros V; Raftopoulos, Vasilios; Gamaletsou, Maria N; Karapanou, Amalia; Koukou, Dimitra-Maria; Koutsidou, Athanasia; Peskelidou, Emmanuela; Papanastasiou, Konstantina; Souliotis, Kyriakos; Lourida, Athanasia; Sipsas, Nikolaos V; Hatzigeorgiou, Dimitrios.
  • Maltezou HC; Directorate of Research, Studies and Documentation, National Public Health Organization, Athens, Greece. Electronic address: helen-maltezou@ath.forthnet.gr.
  • Panagopoulos P; Second Department of Internal Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
  • Sourri F; Department of Infection Control, 251 Hellenic Air Force General Hospital, Athens, Greece.
  • Giannouchos TV; Department of Health Services Policy and Management, Arnold School of Public Health, University of South Carolina, Columbia, SC, United States.
  • Raftopoulos V; Department of HIV Surveillance, National Public Health Organization, Athens, Greece.
  • Gamaletsou MN; Pathophysiology Department, Medical School, National and Kapodistrian University of Athens, Greece.
  • Karapanou A; Infection Control Committee, Laiko General Hospital, Athens, Greece.
  • Koukou DM; First Department of Pediatrics, University of Athens, Aghia Sophia Children's Hospital, Athens, Greece.
  • Koutsidou A; Infection Control Committee, Alexandroupolis University Hospital, Alexandroupolis, Greece.
  • Peskelidou E; COVID-19 Intensive Care Unit, 424 General Military Hospital of Thessaloniki, Thessaloniki, Greece.
  • Papanastasiou K; Operating Rooms, 424 General Military Hospital of Thessaloniki, Thessaloniki, Greece.
  • Souliotis K; Faculty of Social and Political Sciences, University of Peloponnese, Corinth, Greece; Health Policy Institute, Athens, Greece.
  • Lourida A; Infection Control Committee, Aghia Sofia Children's Hospital, Athens, Greece.
  • Sipsas NV; Pathophysiology Department, Medical School, National and Kapodistrian University of Athens, Greece.
  • Hatzigeorgiou D; Medical Directorate, Hellenic National Defence General Staff, Athens, Greece.
Vaccine ; 39(48): 7021-7027, 2021 11 26.
Article in English | MEDLINE | ID: covidwho-1487999
ABSTRACT

AIM:

Healthcare personnel (HCP) are prioritized for coronavirus disease 2019 (COVID-19) vaccination to protect them and non-disruptive provision of healthcare services. We assessed the impact of the Pfizer-BioNTech vaccine on morbidity and absenteeism among HCP.

METHODS:

We studied 7445 HCP in five tertiary-care hospitals in Greece from November 15, 2020 through April 18, 2021.

RESULTS:

A total of 910 episodes of absenteeism and 9695 days of absence were recorded during the entire study period. Starting from January 4, 2021, 4823/7445 HCP (64.8%) were fully or partially vaccinated. Overall, 535 episodes of absenteeism occurred from January 4, 2021 through April 18, 2021, including 309 (57.76%) episodes among 2622 unvaccinated HCP and 226 (42.24%) episodes among 4823 vaccinated HCP (11.8 versus 4.7 episodes of absenteeism per 100 HCP, respectively; p-value < 0.001). The mean duration of absenteeism was 11.9 days among unvaccinated HCP compared with 6.9 days among vaccinated HCP (p-value < 0.001). Unvaccinated HCP more frequently developed acute respiratory infection, influenza-like illness, and COVID-19 (p-values < 0.001 for all comparisons). Vaccine effectiveness for fully vaccinated HCP was estimated at 94.16% [confidence interval (CI) 88.50%-98.05%) against COVID-19, 83.62% (CI 73.36%-90.38%) against SARS-CoV-2 infection (asymptomatic or COVID-19), and 66.42% (CI 56.86%-74.15%) against absenteeism.

CONCLUSION:

The COVID-19 pandemic had a considerable impact on healthcare workforce. The Pfizer-BioNTech vaccine significantly reduced morbidity, COVID-19, absenteeism and duration of absenteeism among HCP during a period of high SARS-CoV-2 circulation in the community. It is expected that HCP vaccination will protect them and healthcare services and contain healthcare costs.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Absenteeism / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: Vaccine Year: 2021 Document Type: Article

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Absenteeism / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: Vaccine Year: 2021 Document Type: Article