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Transfer of chemicals to a secondary container, from the introduction of new labelling regulation to COVID-19 lockdown: A retrospective analysis of exposure calls to the Poison Control Centre of Rome, Italy, 2017-2020.
Milella, Michele Stanislaw; Grassi, Maria Caterina; Gasbarri, Alessia; Mezzanotte, Valeria; Pugliese, Francesco; Vivino, Gabriella.
  • Milella MS; Poison Control Centre Unit, Department of Emergency, Anesthesia and Critical Care Medicine, Policlinico Umberto I Hospital-Sapienza, University of Rome, Rome, Italy.
  • Grassi MC; Department of Physiology and Pharmacology "V. Erspamer", Sapienza University of Rome, Rome, Italy.
  • Gasbarri A; Department of Physiology and Pharmacology "V. Erspamer", Sapienza University of Rome, Rome, Italy.
  • Mezzanotte V; Poison Control Centre Unit, Department of Emergency, Anesthesia and Critical Care Medicine, Policlinico Umberto I Hospital-Sapienza, University of Rome, Rome, Italy.
  • Pugliese F; Poison Control Centre Unit, Department of Emergency, Anesthesia and Critical Care Medicine, Policlinico Umberto I Hospital-Sapienza, University of Rome, Rome, Italy.
  • Vivino G; Department of Emergency, Anesthesia and Critical Care Medicine, Policlinico Umberto I Hospital-Sapienza, University of Rome, Rome, Italy.
Basic Clin Pharmacol Toxicol ; 130(1): 200-207, 2022 Jan.
Article in English | MEDLINE | ID: covidwho-1488179
ABSTRACT
The transfer of a chemical product from its original container to an unlabelled secondary container by consumers is a potential health hazard that may result in unintentional exposures and intoxications. The aim of this study was to describe the pattern of prevalence of exposures to transferred products in Italy from year 2017, when the new European labelling regulation for chemicals became fully operative, to 2020, year of the coronavirus 19 disease first outbreak. Calls to the Poison Control Centre (PCC) of Policlinico Umberto I Hospital - Sapienza University of Rome were analysed retrospectively for characteristics, clinical presentation and circumstances related to the event. We registered 198 cases of interest. There was a reduction in cases from 2017 (4.9%) to 2019 (2.2%), followed by an increased prevalence in 2020 (4.2%) mainly due to the months "post-lockdown." The transferred product was very frequently diluted, and an empty drinking bottle was usually used as secondary container. Exposures were mostly of minor severity, and no deaths occurred. The study highlights the importance of PCCs data in the evaluation of the hazard communication to users through labels and advises for public campaigns to promote safe behaviours during future lockdowns to prevent exposures at a later period.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Poisoning / Product Labeling / Hazardous Substances / Environmental Exposure / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Basic Clin Pharmacol Toxicol Journal subject: Pharmacology / Toxicology Year: 2022 Document Type: Article Affiliation country: Bcpt.13678

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Poisoning / Product Labeling / Hazardous Substances / Environmental Exposure / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Basic Clin Pharmacol Toxicol Journal subject: Pharmacology / Toxicology Year: 2022 Document Type: Article Affiliation country: Bcpt.13678