Impact of Lung Segmentation on the Diagnosis and Explanation of COVID-19 in Chest X-ray Images.
Sensors (Basel)
; 21(21)2021 Oct 27.
Article
in English
| MEDLINE | ID: covidwho-1488701
ABSTRACT
COVID-19 frequently provokes pneumonia, which can be diagnosed using imaging exams. Chest X-ray (CXR) is often useful because it is cheap, fast, widespread, and uses less radiation. Here, we demonstrate the impact of lung segmentation in COVID-19 identification using CXR images and evaluate which contents of the image influenced the most. Semantic segmentation was performed using a U-Net CNN architecture, and the classification using three CNN architectures (VGG, ResNet, and Inception). Explainable Artificial Intelligence techniques were employed to estimate the impact of segmentation. A three-classes database was composed lung opacity (pneumonia), COVID-19, and normal. We assessed the impact of creating a CXR image database from different sources, and the COVID-19 generalization from one source to another. The segmentation achieved a Jaccard distance of 0.034 and a Dice coefficient of 0.982. The classification using segmented images achieved an F1-Score of 0.88 for the multi-class setup, and 0.83 for COVID-19 identification. In the cross-dataset scenario, we obtained an F1-Score of 0.74 and an area under the ROC curve of 0.9 for COVID-19 identification using segmented images. Experiments support the conclusion that even after segmentation, there is a strong bias introduced by underlying factors from different sources.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Deep Learning
/
COVID-19
Type of study:
Experimental Studies
/
Prognostic study
/
Randomized controlled trials
Limits:
Humans
Language:
English
Year:
2021
Document Type:
Article
Affiliation country:
S21217116
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