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Association of blood glucose level and prognosis of inpatients with coexistent diabetes and COVID-19.
Duan, Weiwei; Li, Liangyu; Li, Xuesong; Zhu, Mengyan; Wu, Lingxiang; Wu, Wei; Li, Kening; Liang, Yuan; Ding, Rong; You, Wenhua; Wang, Ziyu; Huang, Bin; Wu, Min; Zhang, Tingting; Li, Jie; Li, Yan; Shao, Jiaofang; Lin, Changsong; Li, Pengping; Wang, Qianghu; Wang, Shukui; Xia, Xinyi; Liu, Yu; Lyu, Sali.
  • Duan W; Research Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China. passion@njmu.edu.cn.
  • Li L; Department of Bioinformatics, Nanjing Medical University, Nanjing, China. passion@njmu.edu.cn.
  • Li X; Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing, China. passion@njmu.edu.cn.
  • Zhu M; Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Personalized Cancer Medicine, Nanjing Medical University, Nanjing, China. passion@njmu.edu.cn.
  • Wu L; Research Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
  • Wu W; Department of Bioinformatics, Nanjing Medical University, Nanjing, China.
  • Li K; Key Laboratory of Cardiovascular and Cerebrovascular Medicine, School of Pharmacy, Nanjing Medical University, Nanjing, China.
  • Liang Y; Research Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
  • Ding R; Department of Bioinformatics, Nanjing Medical University, Nanjing, China.
  • You W; Research Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
  • Wang Z; Department of Bioinformatics, Nanjing Medical University, Nanjing, China.
  • Huang B; Research Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
  • Wu M; Department of Bioinformatics, Nanjing Medical University, Nanjing, China.
  • Zhang T; Research Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
  • Li J; Department of Bioinformatics, Nanjing Medical University, Nanjing, China.
  • Li Y; Research Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
  • Shao J; Department of Bioinformatics, Nanjing Medical University, Nanjing, China.
  • Lin C; Research Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
  • Li P; Department of Bioinformatics, Nanjing Medical University, Nanjing, China.
  • Wang Q; Research Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
  • Wang S; Department of Bioinformatics, Nanjing Medical University, Nanjing, China.
  • Xia X; Research Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
  • Liu Y; Department of Bioinformatics, Nanjing Medical University, Nanjing, China.
  • Lyu S; Research Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
Endocrine ; 75(1): 1-9, 2022 01.
Article in English | MEDLINE | ID: covidwho-1491380
ABSTRACT
Type 2 diabetes (T2D) increases the risk of coronavirus disease (COVID-19). This study investigates the association between glucose control of COVID-19 patients with T2D in first 7 days after hospital admission and prognosis. A total of 252 infected inpatients with T2D in China were included. Well-controlled blood glucose was defined as stable fasting blood glucose (FBG) levels in the range of 3.9-7.8 mmol/L during first 7 days using indicators of average (FBGA), maximum (FBGM) or first-time (FBG1) FBG levels. The primary endpoint was admission to intensive care unit or death. Hazard ratio (HR) of poorly controlled glucose level group compared with well-controlled group were 4.96 (P = 0.021) for FBGM and 5.55 (P = 0.014) for FBGA. Well-controlled blood glucose levels in first 7 days could improve the prognosis of COVID-19 inpatients with diabetes.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Diabetes Mellitus, Type 2 / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Endocrine Journal subject: Endocrinology Year: 2022 Document Type: Article Affiliation country: S12020-021-02923-7

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Diabetes Mellitus, Type 2 / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Endocrine Journal subject: Endocrinology Year: 2022 Document Type: Article Affiliation country: S12020-021-02923-7