Low-concentration povidone-iodine for the prevention of intraocular infections in ophthalmic surgery.
Curr Opin Ophthalmol
; 33(1): 28-34, 2022 Jan 01.
Article
in English
| MEDLINE | ID: covidwho-1494046
ABSTRACT
PURPOSE OF REVIEW Endophthamitis following intraocular surgery is rare using current antiseptic techniques, such as single application of 5% povidone-iodine to the ocular surface and adjuvant topical or intracameral antibiotics. Challenges remain, however, including increased multidrug-resistant bacterial endophthalmitis, increased fungal endophthalmitis, and the low but nonzero endophthalmitis rate attributable to the typical bacteria that colonize the ocular surface. RECENT FINDINGS:
Povidone-iodine has a wide spectrum of activity, including activity against novel pathogens, such as SARS-CoV-2. Povidone-iodine alternatives, such as hypochlorous acid can have significantly less efficacy in vitro against endophthalmitis isolates. Repetitive application of dilute povidone-iodine has an excellent safety profile and strong evidence base for efficacy.SUMMARY:
Povidone-iodine is widely available, inexpensive, and commonly used by ophthalmologists. The repetitive application of dilute povidone-iodine is a well studied, well tolerated, and efficacious way to transiently sterilize the ocular surface during intraocular surgery. Additional benefits include activity against multidrug-resistant bacteria, fungi, and lack of inducible resistance.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Endophthalmitis
/
COVID-19
/
Anti-Infective Agents, Local
Limits:
Humans
Language:
English
Journal:
Curr Opin Ophthalmol
Journal subject:
Ophthalmology
Year:
2022
Document Type:
Article
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