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SARS CoV-2 seroprevalence in a US school district during COVID-19.
Bullis, Sean S M; Grebber, Benjamin; Cook, Sally; Graham, Nancy R; Carmolli, Marya; Dickson, Dorothy; Diehl, Sean A; Kirkpatrick, Beth D; Lee, Benjamin.
  • Bullis SSM; Department of Medicine, University of Vermont College of Medicine, Burlington, Vermont, USA.
  • Grebber B; University of Vermont College of Medicine, Burlington, VT, USA.
  • Cook S; Vermont Department of Health, Burlington, Vermont, USA.
  • Graham NR; Department of Microbiology and Molecular Genetics, University of Vermont College of Medicine, Burlington, Vermont, USA.
  • Carmolli M; Department of Microbiology and Molecular Genetics, University of Vermont College of Medicine, Burlington, Vermont, USA.
  • Dickson D; Department of Microbiology and Molecular Genetics, University of Vermont College of Medicine, Burlington, Vermont, USA.
  • Diehl SA; Department of Microbiology and Molecular Genetics, University of Vermont College of Medicine, Burlington, Vermont, USA.
  • Kirkpatrick BD; Department of Medicine, University of Vermont College of Medicine, Burlington, Vermont, USA.
  • Lee B; Department of Microbiology and Molecular Genetics, University of Vermont College of Medicine, Burlington, Vermont, USA.
BMJ Paediatr Open ; 5(1): e001259, 2021.
Article in English | MEDLINE | ID: covidwho-1495481
ABSTRACT
Reduced symptomatology and access to testing in children have led to underestimates of paediatric COVID-19 prevalence and raised concerns about school safety. To explore COVID-19 prevalence and risk factors in school settings, we conducted a SARS-CoV-2 serosurvey in a Vermont, USA school district in December 2020. Among 336 students (63%) and 196 teachers/staff (37%), adjusted seroprevalence was 4.7% (95% CI 2.9 to 7.2) and was lowest in preK-5 students (4-10 Years). Seroprevalence was 10-fold higher than corresponding state PCR data but was low overall with no evidence of onward transmissions. These results further support feasibility of in-person learning during COVID-19 with appropriate mitigation measures.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Observational study / Prognostic study Limits: Child / Humans Language: English Journal: BMJ Paediatr Open Year: 2021 Document Type: Article Affiliation country: Bmjpo-2021-001259

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Observational study / Prognostic study Limits: Child / Humans Language: English Journal: BMJ Paediatr Open Year: 2021 Document Type: Article Affiliation country: Bmjpo-2021-001259