Discontinuation of Antihypertensive Medications on the Outcome of Hospitalized Patients With Severe Acute Respiratory Syndrome-Coronavirus 2.

Singh, Sandeep; Offringa-Hup, Annette K; Logtenberg, Susan J J; Van der Linden, Paul D; Janssen, Wilbert M T; Klein, Hubertina; Waanders, Femke; Simsek, Suat; de Jager, Cornelis P C; Smits, Paul; van der Feltz, Machteld; Jan Beumer, Gerrit; Widrich, Christine; Nap, Martijn; Pinto-Sietsma, Sara-Joan

Singh, Sandeep; Offringa-Hup, Annette K; Logtenberg, Susan J J; Van der Linden, Paul D; Janssen, Wilbert M T; Klein, Hubertina; Waanders, Femke; Simsek, Suat; de Jager, Cornelis P C; Smits, Paul; van der Feltz, Machteld; Jan Beumer, Gerrit; Widrich, Christine; Nap, Martijn; Pinto-Sietsma, Sara-Joan.

Singh S; From the Department of Clinical Epidemiology, Biostatistics and Bioinformatics (S.S., S.-J.P.-S.), Amsterdam UMC, Academic Medical Center Amsterdam, the Netherlands.
Offringa-Hup AK; Department of Vascular Medicine (S.S., S.-J.P.-S.), Amsterdam UMC, Academic Medical Center Amsterdam, the Netherlands.
Logtenberg SJJ; Microbiology and System Biology, Netherlands Organization for Applied Scientific Research, the Hague (A.K.O.-H.).
Van der Linden PD; Department of Internal Medicine, Diakonessenhuis, Utrecht, the Netherlands (S.J.J.L.).
Janssen WMT; Department of Clinical Pharmacy, Tergooi, the Netherlands (P.D.V.d.L.).
Klein H; Department of Internal Medicine, Martini Hospital, the Netherlands (W.M.T.J.).
Waanders F; Department of Internal Medicine, Slingeland Hospital, Doetinchem, the Netherlands (H.K.).
Simsek S; Department of Internal Medicine, Isala, Zwolle, the Netherlands (F.W.).
de Jager CPC; Department of Internal Medicine/Endocrinology, Northwest Clinics, Alkmaar, the Netherlands (S.S.).
Smits P; Department of Internal Medicine/Endocrinology, Amsterdam UMC, VU University Medical Center, the Netherlands (S.S.).
van der Feltz M; Department of Intensive Care Medicine, Jeroen Bosch Ziekenhuis, the Netherlands (C.P.C.d.J.).
Jan Beumer G; Department of Pharmacology and Toxicology, Radboud university medical center, Radboud Institute for Health Sciences, the Netherlands (P.S.).
Widrich C; Department of Internal Medicine, Alrijne Hospital, Leiderdorp, the Netherlands (M.v.d.F.).
Nap M; Life Sciences TNO, Leiden, the Netherlands (G.J.B.).
Pinto-Sietsma SJ; IQVIA, Amsterdam, the Netherlands (C.W., M.N.).

Hypertension ; 78(1): 165-173, 2021 07.

Article in English | MEDLINE | ID: covidwho-1495765

ABSTRACT

ABSTRACT

[Figure see text].

Subject(s)

Antihypertensive Agents/pharmacology; COVID-19/mortality; Hypertension/drug therapy; Renin-Angiotensin System/drug effects; Adrenergic beta-Antagonists/pharmacology; Adrenergic beta-Antagonists/therapeutic use; Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists/pharmacology; Angiotensin Receptor Antagonists/therapeutic use; Angiotensin-Converting Enzyme Inhibitors/pharmacology; Angiotensin-Converting Enzyme Inhibitors/therapeutic use; Antihypertensive Agents/therapeutic use; COVID-19/complications; COVID-19/physiopathology; Female; Hospitalization; Humans; Hypertension/complications; Male; Middle Aged; Retrospective Studies; SARS-CoV-2; Treatment Outcome; Withholding Treatment

Keywords

angiotensins; coronary artery disease; diuretics; obesity; pandemic

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Renin-Angiotensin System / COVID-19 / Hypertension / Antihypertensive Agents Type of study: Observational study / Prognostic study Topics: Long Covid Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: Hypertension Year: 2021 Document Type: Article Affiliation country: HYPERTENSIONAHA.121.17328

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