Frequency and factors associated with proteinuria in COVID-19 patients: a cross-sectional study.
Pan Afr Med J
; 40: 37, 2021.
Article
in English
| MEDLINE | ID: covidwho-1497891
ABSTRACT
Proteinuria is a marker of severity and poor outcome of patients in intensive care unit (ICU). The objective of this study was to determine the frequency of proteinuria and the risk factors associated with proteinuria in Congolese COVID-19 patients. The present cross sectional study of proteinuria status is a post hoc analysis of data from 80 COVID-19 patients admitted at Kinshasa Medical Center (KMC) from March 10th to July 10th, 2020. The population under study came from all adult inpatients (≥18 years old) with a laboratory diagnosis by polymerase chain reaction (PCR) of COVID-19 were selected and divided into two groups (positive proteinuria and negative proteinuria group). Logistic regression models helped to identify the factors associated with proteinuria. The P value significance level was 0.05. Among 80 patients who tested positive for SARS-CoV-2 RT-PCR, 55% had proteinuria. The mean age was 55.2 ± 12.8 years. Fourty-seven patients (58.8%) had history of hypertension and 26 patients (32.5%) diabetes. Multivariable analysis showed age ≥ 65 years (aOR 5,04; 95% CI 1.51-16.78), diabetes (aOR 3,15; 95% CI 1.14-8.72), ASAT >40 UI/L (aOR 7,08; 95% CI 2.40-20.87), ferritin >300 (aOR 13,47; 95% CI 1.56-26.25) as factors independently associated with proteinuria in COVID-19 patients. Proteinuria is common in Congolese COVID-19 patients and is associated with age, diabetes, ferritin and aspartate aminotransferase (ASAT).
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Proteinuria
/
Diabetes Mellitus
/
COVID-19
/
Hypertension
Type of study:
Diagnostic study
/
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Topics:
Long Covid
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Africa
Language:
English
Journal:
Pan Afr Med J
Year:
2021
Document Type:
Article
Affiliation country:
Pamj.2021.40.37.29796
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