SARS-CoV-2 infection in lung transplant recipients induces circulating exosomes with SARS-CoV-2 spike protein S2.

Bansal, Sandhya; Tokman, Sofya; Fleming, Timothy; Maine, Gabriel N; Sanborn, Kristina; Hachem, Ramsey; Bharat, Ankit; Smith, Michael A; Bremner, Ross M; Mohanakumar, T

Bansal, Sandhya; Tokman, Sofya; Fleming, Timothy; Maine, Gabriel N; Sanborn, Kristina; Hachem, Ramsey; Bharat, Ankit; Smith, Michael A; Bremner, Ross M; Mohanakumar, T.

Bansal S; Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona.
Tokman S; Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona.
Fleming T; Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona.
Maine GN; Department of Pathology and Laboratory Medicine, Beaumont Health, Royal Oak, Michigan.
Sanborn K; Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona.
Hachem R; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Bharat A; Department of Surgery, Northwestern University, Chicago, Illinois.
Smith MA; Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona.
Bremner RM; Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona.
Mohanakumar T; Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona.

Clin Transl Med ; 11(11): e576, 2021 11.

Article in English | MEDLINE | ID: covidwho-1499248

Subject(s)

COVID-19/pathology; Exosomes/metabolism; Lung Transplantation; Spike Glycoprotein, Coronavirus/metabolism; Asymptomatic Diseases; Blotting, Western; COVID-19/virology; Humans; Mass Spectrometry; Microscopy, Electron, Transmission; Nucleocapsid Proteins/chemistry; Nucleocapsid Proteins/immunology; Nucleocapsid Proteins/metabolism; Protein Subunits/chemistry; Protein Subunits/immunology; Protein Subunits/metabolism; SARS-CoV-2/isolation & purification; SARS-CoV-2/metabolism; Spike Glycoprotein, Coronavirus/chemistry; Spike Glycoprotein, Coronavirus/immunology

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Lung Transplantation / Exosomes / Spike Glycoprotein, Coronavirus / COVID-19 Limits: Humans Language: English Journal: Clin Transl Med Year: 2021 Document Type: Article

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