Severe respiratory viral infections in children with history of asymptomatic or mild COVID-19.
Pediatr Pulmonol
; 57(2): 361-366, 2022 02.
Article
in English
| MEDLINE | ID: covidwho-1499312
ABSTRACT
IMPORTANCE The spectrum of complications of COVID-19 in children, including the effect of COVID-19 on later viral infection, is not known. OBJECTIVE:
To examine the features of children hospitalized for respiratory illness with history of prior COVID-19.DESIGN:
Retrospective observational case series at a single pediatric quaternary medical center in New York City. Data were obtained from review of medical records.PARTICIPANTS:
Children with prior mild or asymptomatic COVID-19 and no known risk factors for severe respiratory disease, who were hospitalized at our center for acute respiratory illness from October 2020 to May 2021, were reviewed. MAIN OUTCOMES ANDMEASURES:
Co-morbidities, history of prior COVID-19 symptoms, respiratory viral panel findings, acuity of illness, degree of respiratory decompensation based on support and interventions required, duration of hospitalization, and overall clinical course were assessed from the medical record.RESULTS:
This study included 5 patients (median age, 4 years; age range 0.8-9 years; 4 [80%] male). All had positive COVID-19 serology, 1 (20%) had mild symptoms, while the others had no symptoms of prior Sars-CoV-2 infection, 3 (60%) had asthma, and the remaining had no co-morbidities. All were admitted between April and May 2021. Two were re-admitted for respiratory symptoms in the subsequent 3 months. CONCLUSIONS AND RELEVANCE This case series describes a possible association between severe lower respiratory tract infection and prior mild COVID-19 in children. Larger cohort studies describing the respiratory effects of prior COVID-19 in children are needed.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Virus Diseases
/
COVID-19
Type of study:
Cohort study
/
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
English
Journal:
Pediatr Pulmonol
Journal subject:
Pediatrics
Year:
2022
Document Type:
Article
Affiliation country:
Ppul.25752
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