Illness severity indicators in newborns by COVID-19 status in the United States, March-December 2020.
J Perinatol
; 42(4): 446-453, 2022 04.
Article
in English
| MEDLINE | ID: covidwho-1500442
ABSTRACT
OBJECTIVE:
To better understand COVID-19 in newborns, we compared in-hospital illness severity indicators by COVID-19 status during birth hospitalization. STUDYDESIGN:
In a retrospective cohort of newborns born March-December 2020 in the Premier Healthcare Database Special COVID-19 Release, we classified COVID-19 status and severe illness indicators using ICD-CM-10 codes, laboratory data, and billing records. Illness severity indicators were compared by COVID-19 status, stratified by gestational age and race/ethnicity.RESULT:
Among 701,777 newborns, 209 had a COVID-19 diagnosis during the birth hospitalization. COVID-19 status differed significantly by race/ethnicity, gestational age, payor, and region. Late preterm/term newborns with COVID-19 had increased intensive care unit admission and sepsis risk; early preterm newborns with COVID-19 had increased risk for invasive ventilation. Risk for illness severity varied among racial/ethnic strata.CONCLUSION:
From March to December 2020, COVID-19 diagnosis in newborns was rare. More clinical data are needed to describe the risk profiles of newborns with COVID-19.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
Type of study:
Cohort study
/
Diagnostic study
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Humans
/
Infant, Newborn
Country/Region as subject:
North America
Language:
English
Journal:
J Perinatol
Journal subject:
Perinatology
Year:
2022
Document Type:
Article
Affiliation country:
S41372-021-01243-y
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