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Beyond the 405 and the 5: Geographic Variations and Factors Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Positivity Rates in Los Angeles County.
Vijayan, Tara; Shin, Michael; Adamson, Paul C; Harris, Christina; Seeman, Teresa; Norris, Keith C; Goodman-Meza, David.
  • Vijayan T; Division of Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, California, USA.
  • Shin M; Department of Geography, UCLA, Los Angeles, California, USA.
  • Adamson PC; Division of Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, California, USA.
  • Harris C; VA Greater Los Angeles Healthcare System, David Geffen School of Medicine, UCLA, Los Angeles, California, USA.
  • Seeman T; Division of Geriatrics, David Geffen School of Medicine, UCLA, Los Angeles, California, USA.
  • Norris KC; Division of General Internal Medicine-Health Services Research, David Geffen School of Medicine, UCLA, Los Angeles, California, USA.
  • Goodman-Meza D; Division of Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, California, USA.
Clin Infect Dis ; 73(9): e2970-e2975, 2021 11 02.
Article in English | MEDLINE | ID: covidwho-1501032
ABSTRACT

BACKGROUND:

To highlight geographic differences and the socio-structural determinants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) test positivity within Los Angeles County (LAC).

METHODS:

A geographic information system was used to integrate, map, and analyze SARS-CoV-2 testing data reported by the LAC Department of Public Health and data from the American Community Survey. Structural determinants included race/ethnicity, poverty, insurance status, education, and population and household density. We examined which factors were associated with positivity rates, using a 5% test positivity threshold, with spatial analysis and spatial regression.

RESULTS:

Between 1 March and 30 June 2020 there were 843 440 SARS-CoV-2 tests and 86 383 diagnoses reported, for an overall positivity rate of 10.2% within the study area. Communities with high proportions of Latino/a residents, those living below the federal poverty line, and with high household densities had higher crude positivity rates. Age- adjusted diagnosis rates were significantly associated with the proportion of Latino/as, individuals living below the poverty line, and population and household density.

CONCLUSIONS:

There are significant local variations in test positivity within LAC and several socio-structural determinants contribute to ongoing disparities. Public health interventions, beyond shelter in place, are needed to address and target such disparities.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Observational study Limits: Humans Country/Region as subject: North America Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: Cid

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Observational study Limits: Humans Country/Region as subject: North America Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: Cid