New-onset celiac disease in children during COVID-19 pandemic.
Acta Paediatr
; 111(2): 383-388, 2022 Feb.
Article
in English
| MEDLINE | ID: covidwho-1501375
ABSTRACT
AIM:
We aimed to analyse the influence of the COVID-19 pandemic on the frequency and clinical presentation of celiac disease.METHODS:
The study included the patients with celiac disease since January 2008. They were divided into 2 groups (diagnosed in pre-pandemic [January 2008 and February 2020] [n = 148] and in pandemic period [March 2020 and June 2021] [n = 47]). Clinical and histological findings were compared between groups. Additionally, data about severe acute respiratory syndrome coronavirus 2 infection were obtained in subgroup patients (n = 22) with celiac disease diagnosed during pandemic period.RESULTS:
The number of patients per year (12.1-37.6) and the percentage of patients who were diagnosed with celiac disease/total endoscopy were increased during the pandemic period (2.2% vs. 10%, p < 0.00001). The association of celiac disease with type 1 diabetes mellitus was significantly high in pandemic period (4% vs. 17%, p = 0.002). Frequency of moderate-severe mucosal lesions was low in pandemic period (42.4% vs. 81.7%, p = 0.0001). Clinical and laboratory markers for the past severe acute respiratory syndrome coronavirus 2 infection were found in 36.3% of patients diagnosed during the pandemic period.CONCLUSION:
It seems that the frequency of celiac disease and its association with type 1 diabetes mellitus is increased during the COVID-19 pandemic in children.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Celiac Disease
/
Diabetes Mellitus, Type 1
/
COVID-19
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Topics:
Long Covid
Limits:
Child
/
Humans
Language:
English
Journal:
Acta Paediatr
Year:
2022
Document Type:
Article
Affiliation country:
Apa.16173
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