Taming the Storm in the Heart: Exploring Different Therapeutic Choices Against Myocardial Inflammation in COVID-19.
Recent Adv Antiinfect Drug Discov
; 16(2): 89-93, 2021.
Article
in English
| MEDLINE | ID: covidwho-1502217
ABSTRACT
Mechanism of cardiac injury in COVID-19 is a serious problem and plays critical role in mediating the severity of the disease. However, the mechanistic insights of the induction of the inflammatory signal leading to cardiac injury was poorly understood. However, few recent studies have indicated the involvement of Toll-Like Receptors (TLRs) as the major 'culprit' behind eliciting the initial signal of 'cytokine storm'. As a result, TLRs are now considered as the therapeutic targets to develop efficacious therapeutics. Herein, we present an overall summary on the mechanistic insight of cardiac injury in COVID-19 patients and the therapeutic promises of TLR-targeted therapies.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19 Drug Treatment
/
Myocarditis
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Recent Adv Antiinfect Drug Discov
Year:
2021
Document Type:
Article
Affiliation country:
2772434416666210616124505
Similar
MEDLINE
...
LILACS
LIS