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Evaluation of hepatic morphology in rats after administration of strontium ranelate
Information and Documentation [CC300] Animal Models of Human Diseases [VV400] Non-communicable Human Diseases and Injuries [VV600] Occupational Health and Safety [VV900] administration adverse effects animal models bone diseases bone formation bones cirrhosis disease prevalence disease prevention effects evaluation fibrosis formaldehyde hepatitis hyperplasia incidence laboratory animals liver liver diseases morphology osteoporosis parenchyma prophylaxis strontium viral diseases rats Muridae rodents mammals vertebrates Chordata animals eukaryotes Severe acute respiratory syndrome coronavirus 2 adverse reactions bone calcification liver cirrhosis viral infections ; 2020(Revista de Ciencias Medicas e Biologicas)
Article in Portuguese | WHO COVID | ID: covidwho-1502769
ABSTRACT

Introduction:

the drug strontium ranelate (SR) is widely used in prophylactic therapy and in the control of osteoporosis. It acts by reducing reabsorption and increasing bone formation systemically, presenting unclear adverse events in the literature, such as the DRESS syndrome with hepatic involvement.
Full text: Available Collection: Databases of international organizations Database: WHO COVID Type of study: Experimental Studies Language: Portuguese Journal: Information and Documentation [CC300] Animal Models of Human Diseases [VV400] Non-communicable Human Diseases and Injuries [VV600] Occupational Health and Safety [VV900] administration adverse effects animal models bone diseases bone formation bones cirrhosis disease prevalence disease prevention effects evaluation fibrosis formaldehyde hepatitis hyperplasia incidence laboratory animals liver liver diseases morphology osteoporosis parenchyma prophylaxis strontium viral diseases rats Muridae rodents mammals vertebrates Chordata animals eukaryotes Severe acute respiratory syndrome coronavirus 2 adverse reactions bone calcification liver cirrhosis viral infections Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: WHO COVID Type of study: Experimental Studies Language: Portuguese Journal: Information and Documentation [CC300] Animal Models of Human Diseases [VV400] Non-communicable Human Diseases and Injuries [VV600] Occupational Health and Safety [VV900] administration adverse effects animal models bone diseases bone formation bones cirrhosis disease prevalence disease prevention effects evaluation fibrosis formaldehyde hepatitis hyperplasia incidence laboratory animals liver liver diseases morphology osteoporosis parenchyma prophylaxis strontium viral diseases rats Muridae rodents mammals vertebrates Chordata animals eukaryotes Severe acute respiratory syndrome coronavirus 2 adverse reactions bone calcification liver cirrhosis viral infections Document Type: Article