Factors influencing IgG response against SARS-CoV-2: a quantitative serological survey among healthcare workers of a COVID-19 dedicated health facility in India

ABSTRACT

Objectives: The objectives of the study were to explore the factors influencing serum IgG response against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) among healthcare workers (HCWs) of a tertiary healthcare facility in India. Material and Methods: It was a monocentric, observational study during the month of September 2020. In the study, a cross-sectional quantitative serological assessment of IgG response against SARS-CoV-2 among HCWs of All India Institute of Medical Sciences (AIIMS), Patna, Bihar, was done using a chemiluminescent immunoassay (CLIA) platform named "ADVIA Centaur COV2G." Statistical Package for the Social Sciences (SPSS) (version 22.0) was used for data analysis.