Acute Corneal Epithelial Rejection of LR-CLAL After SARS-CoV-2 Vaccination.
Cornea
; 41(2): 252-253, 2022 Feb 01.
Article
in English
| MEDLINE | ID: covidwho-1505854
ABSTRACT
PURPOSE:
The purpose of this study was to report a case of acute corneal epithelial rejection of living-related conjunctival limbal allograft (LR-CLAL) after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. OBSERVATIONS A 27-year-old woman developed acute epithelial rejection of LR-CLAL 2 weeks after receiving the SARS-CoV-2 vaccine. She received the LR-CLAL transplant 4 years and 7 months previously and had a stable clinical course with no history of rejection. She had an ABO blood group and human leukocyte antigen compatible donor, no systemic comorbidities, and no rejection risk factors.CONCLUSIONS:
The novel SARS-CoV-2 vaccine upregulates the immune system to produce an adaptive immune response. The SARS-CoV-2 vaccine may potentially be associated with increased risk of rejection in those with ocular surface transplants.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Vaccination
/
Limbus Corneae
/
Living Donors
/
Epithelium, Corneal
/
Stem Cell Transplantation
/
2019-nCoV Vaccine mRNA-1273
/
Graft Rejection
Type of study:
Case report
/
Diagnostic study
/
Observational study
/
Prognostic study
Topics:
Vaccines
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Cornea
Year:
2022
Document Type:
Article
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