COVID-19 advanced respiratory physiology (CARP) wearable respiratory monitoring: early insights

ABSTRACT

P24 Figure 1CARP trial wearable respiratory rate, respiratory support and outcome data from 3 patients with severe COVID-19[Figure omitted. See PDF]Results156 patients were screened, with 77 recruited to the CARP trial. 32 patients required non-invasive respiratory support, of which 14 were escalated to mechanical intubation. 17 patients died within trial.Bland-Altman analyses of paired RR data confirmed that wearable sensor data shows good agreement with critical care RR monitoring (Phillips Intellivue MX700), and that ward-based intermittent clinician RR measurements were imprecise.From the initial utility review of CARP physiology data visualisations, rising hourly average RR >25/min is associated with subsequent patient deterioration. Improving and stable hourly average RR of <25/min associates with stable respiratory failure and improvement to hospital discharge (figure 1).ConclusionContinuous wearable respiratory rate remote monitoring in COVID-19 inpatients is feasible. Planned machine learning and time-series analyses of the detailed physiology and clinical endpoint data will determine appropriate cut-offs and feature importance for deteriorating patient risk predictions. The CARP clinical dashboard provides an infrastructure for future implementation and evaluation of these AI insights.