Bioprospecting of microalgae metabolites against cytokine storm syndrome during COVID-19.
Mol Biol Rep
; 49(2): 1475-1490, 2022 Feb.
Article
in English
| MEDLINE | ID: covidwho-1507001
ABSTRACT
In viral respiratory infections, disrupted pathophysiological outcomes have been attributed to hyper-activated and unresolved inflammation responses of the immune system. Integration between available drugs and natural therapeutics have reported benefits in relieving inflammation-related physiological outcomes and microalgae may be a feasible source from which to draw from against future coronavirus-infections. Microalgae represent a large and diverse source of chemically functional compounds such as carotenoids and lipids that possess various bioactivities, including anti-inflammatory properties. Therefore in this paper, some implicated pathways causing inflammation in viral respiratory infections are discussed and juxtaposed along with available research done on several microalgal metabolites. Additionally, the therapeutic properties of some known anti-inflammatory, antioxidant and immunomodulating compounds sourced from microalgae are reported for added clarity.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Microalgae
/
Cytokine Release Syndrome
/
COVID-19
/
Anti-Inflammatory Agents
/
Antioxidants
Topics:
Long Covid
Limits:
Animals
/
Humans
Language:
English
Journal:
Mol Biol Rep
Year:
2022
Document Type:
Article
Affiliation country:
S11033-021-06903-y
Similar
MEDLINE
...
LILACS
LIS