Metagenomic evidence for the co-existence of SARS and H1N1 in patients from 2007-2012 flu seasons in France.
Biosaf Health
; 2021 Nov 09.
Article
in English
| MEDLINE | ID: covidwho-1509610
ABSTRACT
By re-analzying public metagenomic data from 101 patients infected with influenza A virus during the 2007-2012 H1N1 flu seasons in France, we identified 22 samples with SARS-CoV sequences. In 3 of them, the SARS genome sequences could be fully assembled out of each. These sequences are highly similar (99.99% and 99.7%) to the artificially constructed recombinant SARS-CoV (SARSr-CoV) strains generated by the J. Craig Venter Institute in the USA. Moreover, samples from different flu seasons have different SARS-CoV strains, and the divergence between these strains cannot be explained by natural evolution. Our study also shows that retrospective studies using public metagenomic data from past major epidemic outbreaks serve as a genomic strategy for researching the origins or spread of infectious diseases.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Observational study
Language:
English
Year:
2021
Document Type:
Article
Affiliation country:
J.bsheal.2021.11.002
Similar
MEDLINE
...
LILACS
LIS