Your browser doesn't support javascript.
Clinical, radiological and functional outcomes in patients with SARS-CoV-2 pneumonia: a prospective observational study.
Gianella, Pietro; Rigamonti, Elia; Marando, Marco; Tamburello, Adriana; Grazioli Gauthier, Lorenzo; Argentieri, Gianluca; Puligheddu, Carla; Pagnamenta, Alberto; Pons, Marco; Fusi-Schmidhauser, Tanja.
  • Gianella P; Department of Internal Medicine, Ospedale Regionale Di Lugano, Ente Ospedaliero Cantonale, Via Tesserete 46, 6900, Lugano, Switzerland.
  • Rigamonti E; Division of Pneumology, Ospedale Regionale Di Lugano, Ente Ospedaliero Cantonale, Lugano, Switzerland.
  • Marando M; Department of Internal Medicine, Ospedale Regionale Di Lugano, Ente Ospedaliero Cantonale, Via Tesserete 46, 6900, Lugano, Switzerland.
  • Tamburello A; Department of Internal Medicine, Ospedale Regionale Di Lugano, Ente Ospedaliero Cantonale, Via Tesserete 46, 6900, Lugano, Switzerland. marco.marando@eoc.ch.
  • Grazioli Gauthier L; Department of Internal Medicine, Ospedale Regionale Di Lugano, Ente Ospedaliero Cantonale, Via Tesserete 46, 6900, Lugano, Switzerland.
  • Argentieri G; Department of Internal Medicine, Ospedale Regionale Di Lugano, Ente Ospedaliero Cantonale, Via Tesserete 46, 6900, Lugano, Switzerland.
  • Puligheddu C; IIMSI - Radiology Department, Ospedale Regionale Di Lugano, Ente Ospedaliero Cantonale, Lugano, Switzerland.
  • Pagnamenta A; IIMSI - Radiology Department, Ospedale Regionale Di Lugano, Ente Ospedaliero Cantonale, Lugano, Switzerland.
  • Pons M; Department of Intensive Care, Intensive Care Unit Ospedale Regionale Di Mendrisio, Ente Ospedaliero Cantonale, Lugano, Switzerland.
  • Fusi-Schmidhauser T; Unit of Biostatistics, Bellinzona, Ente Ospedaliero Cantonale, Lugano, Switzerland.
BMC Pulm Med ; 21(1): 136, 2021 Apr 26.
Article in English | MEDLINE | ID: covidwho-1511742
ABSTRACT

BACKGROUND:

All over the world, SARS-CoV-2 pneumonia is causing a significant short-term morbidity and mortality, but the medium-term impact on lung function and quality of life of affected patients are still unknown.

METHODS:

In this prospective observational study, 39 patients with SARS-CoV-2 pneumonia were recruited from a single COVID-19 hospital in Southern Switzerland. At three months patients underwent radiological and functional follow-up through CT scan, lung function tests, and 6 min walking test. Furthermore, quality of life was assessed through self-reported questionnaires.

RESULTS:

Among 39 patients with SARS-CoV-2 pneumonia, 32 (82% of all participants) presented abnormalities in CT scan and 25 (64.1%) had lung function tests impairment at three months. Moreover, 31 patients (79.5%) reported a perception of poor health due to respiratory symptoms and all 39 patients showed an overall decreased quality of life.

CONCLUSIONS:

Medium-term follow up at three months of patients diagnosed with SARS-CoV-2 pneumonia shows the persistence of abnormalities in CT scans, a significant functional impairment assessed by lung function tests and a decreased quality of life in affected patients. Further studies evaluating the long-term impact are warranted to guarantee an appropriate follow-up to patients recovering from SARS-CoV-2 pneumonia.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Quality of Life / COVID-19 / Lung Subject: Quality of Life / COVID-19 / Lung Type of study: Observational study / Patient-preference Language: English Journal: BMC Pulm Med Clinical aspect: Prognosis Year: 2021

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Quality of Life / COVID-19 / Lung Subject: Quality of Life / COVID-19 / Lung Type of study: Observational study / Patient-preference Language: English Journal: BMC Pulm Med Clinical aspect: Prognosis Year: 2021
...