Anti-Inflammatory Effects of Curcumin in the Inflammatory Diseases: Status, Limitations and Countermeasures.
Drug Des Devel Ther
; 15: 4503-4525, 2021.
Article
in English
| MEDLINE | ID: covidwho-1511886
ABSTRACT
Curcumin is a natural compound with great potential for disease treatment. A large number of studies have proved that curcumin has a variety of biological activities, among which anti-inflammatory effect is a significant feature of it. Inflammation is a complex and pervasive physiological and pathological process. The physiological and pathological mechanisms of inflammatory bowel disease, psoriasis, atherosclerosis, COVID-19 and other research focus diseases are not clear yet, and they are considered to be related to inflammation. The anti-inflammatory effect of curcumin can effectively improve the symptoms of these diseases and is expected to be a candidate drug for the treatment of related diseases. This paper mainly reviews the anti-inflammatory effect of curcumin, the inflammatory pathological mechanism of related diseases, the regulatory effect of curcumin on these, and the latest research results on the improvement of curcumin pharmacokinetics. It is beneficial to the further study of curcumin and provides new ideas and insights for the development of curcumin anti-inflammatory preparations.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Curcumin
/
SARS-CoV-2
/
COVID-19 Drug Treatment
/
Inflammation
/
Anti-Inflammatory Agents
Type of study:
Experimental Studies
Limits:
Animals
/
Humans
Language:
English
Journal:
Drug Des Devel Ther
Journal subject:
Pharmacology
/
Drug Therapy
Year:
2021
Document Type:
Article
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