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A bibliometric analysis of infectious diseases in patients with liver transplantation in the last decade.
Zhong, Han; Liu, Chun-Yan; Dai, You-Qin; Zhu, Cheng; Le, Ke-Jia; Pang, Xiao-Yun; Li, Yu-Jie; Gu, Zhi-Chun; Yu, Yue-Tian.
  • Zhong H; Department of Pharmacy, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Liu CY; Department of Pharmacy, Ningbo Hangzhou Bay Hospital, Ningbo, China.
  • Dai YQ; Department of Emergency, Minhang District Central Hospital, Shanghai, China.
  • Zhu C; Department of Pharmacy, Ningbo Hangzhou Bay Hospital, Ningbo, China.
  • Le KJ; Department of Disease Prevention and Control, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
  • Pang XY; Department of Pharmacy, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Li YJ; Department of Pharmacy, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Gu ZC; Department of Critical Care Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Yu YT; Department of Pharmacy, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ann Transl Med ; 9(22): 1646, 2021 Nov.
Article in English | MEDLINE | ID: covidwho-1513320
ABSTRACT

BACKGROUND:

A bibliometric analysis was performed to reveal the current status of investigations in infectious diseases in patients with liver transplantation (LT) and to prioritize future research needs.

METHODS:

The present study comprehensively retrieved publications relevant to infectious diseases in LT recipients published between 2010 and 2020. The search was conducted on the Web of Science (WoS) database. A bibliometric analysis was conducted through machine learning and visualization tools, including VOSviewer, Bibliographic Item Co-Occurrence Matrix Builder, and Graphical Clustering Toolkit. Research hotspots and trends in the field were assessed, while the contributions and collaborations of countries, institutions, and authors were documented.

RESULTS:

A total of 691 publications were analyzed. Research output sharply increased in 2015, with a fast drop afterward. "Liver transplantation" was the most frequent keyword, with strong links to "hepatitis C virus" and "infection". Study areas included risk factors of infectious diseases in LT recipients, pathogens causing post-transplantation infections, antibacterial therapy and prophylaxis for peritransplant infection complications, living donor LT, and pediatric LT. The efficacy and safety of direct-acting antivirals (DAAs) for hepatitis C virus (HCV) infection among liver transplant recipients has attracted recent research interest. Didier Samuel was the most productive author, while Xavier Forns was the top-cited author. Shanghai Jiao Tong University was the most productive contributor, and Gilead Sciences was the most cited organization. Moreover, the USA was the greatest contributor. Gastroenterology was the most cited journal, while Liver Transplantation was the most prolific journal.

CONCLUSIONS:

This bibliometric analysis will better understand the research status of infectious complications in LT recipients and forecast future research trends. Priority should be given to identifying risk factors for peritransplantation infections and effective treatments against infectious complications in the coming years.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Language: English Journal: Ann Transl Med Year: 2021 Document Type: Article Affiliation country: Atm-21-2388

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Language: English Journal: Ann Transl Med Year: 2021 Document Type: Article Affiliation country: Atm-21-2388