Impact of COVID-19 on multiple body organ failure: A review

ABSTRACT

COVID-19 is a highly contagious disease caused by Severe Acute Respiratory Syndrome CoronaVirus-2 (SARS-CoV-2) which is a novel single-stranded positive RNA infection which consist of cytokines that activate the pathogenic systems that cause high respiratory pain condition and adversely effect on multiple body organ in humans as per their immunity standards to fight against the virus. SARS-CoV-2 enters the host cell through Angiotensin-Converting Enzyme 2 (ACE 2). ACE 2 is a sub-part of the Renin-Aldosterone Angiotensin System (RAAS) which is intelligently communicated in the kidney, heart, lungs and fatal tissues of the body. The malfunctioning of RAAS in the body leads to hypertension, cardiovascular sicknesses, endocrine system and also affect negatively a brain body communication channel. Treatments on the RAAS structure, thiazolidinedione’s and smoking, toxaemia, kidney, lungs disorder due to the SARS-CoV-2 attack on the host cell and notice the behavioural changes of body organs on the arrival of cytokines that causes multi-organ damage. This paper involves the study of the effects of coronavirus disease on multiple body-organ damages.