Acute urticaria alone after CoronaVac COVID-19 vaccination should not be a contraindication for revaccination.
Clin Exp Dermatol
; 47(4): 735-738, 2022 Apr.
Article
in English
| MEDLINE | ID: covidwho-1515201
ABSTRACT
Patients who develop an immediate allergic reaction within the first 4 h of COVID-19 vaccine injection are recommended not to receive the same vaccine again. This recommendation mainly focuses on the mRNA and adenoviral vector COVID-19 vaccines, but data for whole virus vaccines are unknown. We report seven patients who developed an immediate reaction within 4 h (six had generalized urticaria, one had localized urticaria) after the first vaccination with CoronaVac, the inactivated SARS-CoV-2 vaccine. The results of skin tests and basophil activation tests suggested that spike peptides play a role in exacerbating urticaria in some patients. However, all subjects who developed urticaria within 4 h after CoronaVac vaccination were successfully revaccinated without graded challenge, although recurrent urticaria was common. This preliminary result indicates that acute urticaria alone should not be a contraindication for the second dose of CoronaVac if the supply of alternative vaccines is limited.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Urticaria
/
COVID-19
Topics:
Vaccines
Limits:
Humans
Language:
English
Journal:
Clin Exp Dermatol
Year:
2022
Document Type:
Article
Affiliation country:
Ced.14962
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