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Post-acute COVID-19 syndrome.
Nalbandian, Ani; Sehgal, Kartik; Gupta, Aakriti; Madhavan, Mahesh V; McGroder, Claire; Stevens, Jacob S; Cook, Joshua R; Nordvig, Anna S; Shalev, Daniel; Sehrawat, Tejasav S; Ahluwalia, Neha; Bikdeli, Behnood; Dietz, Donald; Der-Nigoghossian, Caroline; Liyanage-Don, Nadia; Rosner, Gregg F; Bernstein, Elana J; Mohan, Sumit; Beckley, Akinpelumi A; Seres, David S; Choueiri, Toni K; Uriel, Nir; Ausiello, John C; Accili, Domenico; Freedberg, Daniel E; Baldwin, Matthew; Schwartz, Allan; Brodie, Daniel; Garcia, Christine Kim; Elkind, Mitchell S V; Connors, Jean M; Bilezikian, John P; Landry, Donald W; Wan, Elaine Y.
  • Nalbandian A; Division of Cardiology, Department of Medicine, Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
  • Sehgal K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. Kartik_sehgal@dfci.harvard.edu.
  • Gupta A; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA. Kartik_sehgal@dfci.harvard.edu.
  • Madhavan MV; Harvard Medical School, Boston, Massachusetts, USA. Kartik_sehgal@dfci.harvard.edu.
  • McGroder C; Division of Cardiology, Department of Medicine, Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
  • Stevens JS; Clinical Trials Center, Cardiovascular Research Foundation, New York, New York, USA.
  • Cook JR; Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, Connecticut, USA.
  • Nordvig AS; Division of Cardiology, Department of Medicine, Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
  • Shalev D; Clinical Trials Center, Cardiovascular Research Foundation, New York, New York, USA.
  • Sehrawat TS; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
  • Ahluwalia N; Division of Nephrology, Department of Medicine, Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
  • Bikdeli B; Division of Endocrinology, Department of Medicine, Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
  • Dietz D; Department of Neurology, Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
  • Der-Nigoghossian C; Department of Psychiatry, Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, and New York State Psychiatric Institute, New York, New York, USA.
  • Liyanage-Don N; Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Rosner GF; Division of Cardiology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Bernstein EJ; Harvard Medical School, Boston, Massachusetts, USA.
  • Mohan S; Clinical Trials Center, Cardiovascular Research Foundation, New York, New York, USA.
  • Beckley AA; Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, Connecticut, USA.
  • Seres DS; Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Choueiri TK; Division of Infectious Diseases, Department of Medicine, Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
  • Uriel N; Clinical Pharmacy, New York-Presbyterian Hospital/Columbia University Irving Medical Center, New York, New York, USA.
  • Ausiello JC; Department of Medicine, Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
  • Accili D; Division of Cardiology, Department of Medicine, Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
  • Freedberg DE; Division of Rheumatology, Department of Medicine, Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
  • Baldwin M; Division of Nephrology, Department of Medicine, Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
  • Schwartz A; Department of Rehabilitation and Regenerative Medicine, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
  • Brodie D; Institute of Human Nutrition and Division of Preventive Medicine and Nutrition, Department of Medicine, Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
  • Garcia CK; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
  • Elkind MSV; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Connors JM; Harvard Medical School, Boston, Massachusetts, USA.
  • Bilezikian JP; Division of Cardiology, Department of Medicine, Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
  • Landry DW; Division of Endocrinology, Department of Medicine, Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
  • Wan EY; Division of Endocrinology, Department of Medicine, Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
Nat Med ; 27(4): 601-615, 2021 04.
Article in English | MEDLINE | ID: covidwho-1517636
ABSTRACT
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen responsible for the coronavirus disease 2019 (COVID-19) pandemic, which has resulted in global healthcare crises and strained health resources. As the population of patients recovering from COVID-19 grows, it is paramount to establish an understanding of the healthcare issues surrounding them. COVID-19 is now recognized as a multi-organ disease with a broad spectrum of manifestations. Similarly to post-acute viral syndromes described in survivors of other virulent coronavirus epidemics, there are increasing reports of persistent and prolonged effects after acute COVID-19. Patient advocacy groups, many members of which identify themselves as long haulers, have helped contribute to the recognition of post-acute COVID-19, a syndrome characterized by persistent symptoms and/or delayed or long-term complications beyond 4 weeks from the onset of symptoms. Here, we provide a comprehensive review of the current literature on post-acute COVID-19, its pathophysiology and its organ-specific sequelae. Finally, we discuss relevant considerations for the multidisciplinary care of COVID-19 survivors and propose a framework for the identification of those at high risk for post-acute COVID-19 and their coordinated management through dedicated COVID-19 clinics.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Humans Language: English Journal: Nat Med Journal subject: Molecular Biology / Medicine Year: 2021 Document Type: Article Affiliation country: S41591-021-01283-z

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Humans Language: English Journal: Nat Med Journal subject: Molecular Biology / Medicine Year: 2021 Document Type: Article Affiliation country: S41591-021-01283-z