Isolation of 4000 SARS-CoV-2 shows that contagiousness is associated with viral load, not vaccine or symptomatic status.

Boschi, Celine; Aherfi, Sarah; Houhamdi, Linda; Colson, Philippe; Raoult, Didier; Scola, Bernard La

Boschi, Celine; Aherfi, Sarah; Houhamdi, Linda; Colson, Philippe; Raoult, Didier; Scola, Bernard La.

Boschi C; Microbes, Evolution, Phylogeny and Infection (MEPHI), UM63, Institut de Recherche pour le Développement (IRD), Assistance Publique - Hôpitaux de Marseille (AP-HM), Aix-Marseille University, Marseille, France.
Aherfi S; IHU Méditerranée Infection, Marseille, France.
Houhamdi L; Microbes, Evolution, Phylogeny and Infection (MEPHI), UM63, Institut de Recherche pour le Développement (IRD), Assistance Publique - Hôpitaux de Marseille (AP-HM), Aix-Marseille University, Marseille, France.
Colson P; IHU Méditerranée Infection, Marseille, France.
Raoult D; IHU Méditerranée Infection, Marseille, France.
Scola B; Microbes, Evolution, Phylogeny and Infection (MEPHI), UM63, Institut de Recherche pour le Développement (IRD), Assistance Publique - Hôpitaux de Marseille (AP-HM), Aix-Marseille University, Marseille, France.

Emerg Microbes Infect ; 10(1): 2276-2278, 2021 Dec.

Article in English | MEDLINE | ID: covidwho-1522076

ABSTRACT

ABSTRACT

Culture inoculation of 6722 nasopharyngeal samples since February 2020 allowed isolation of 3637 SARS-CoV-2 and confirmed that isolation rate is correlated to viral load, regardless symptomatology or vaccination status. Moreover, the delta variant is associated with higher viral loads and therefore higher rates of viral isolation, explaining its greater contagiousness.

Subject(s)

COVID-19/virology; SARS-CoV-2/physiology; Viral Load; Adult; Aged; Aged, 80 and over; COVID-19/prevention & control; COVID-19/transmission; COVID-19 Vaccines/administration & dosage; COVID-19 Vaccines/genetics; COVID-19 Vaccines/immunology; Female; Humans; Male; Middle Aged; Nasopharynx/virology; SARS-CoV-2/genetics; SARS-CoV-2/isolation & purification; Vaccination

Keywords

SARS-CoV-2; culture; delta variant; symptomatology; vaccination

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Viral Load / SARS-CoV-2 / COVID-19 Topics: Vaccines / Variants Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: Emerg Microbes Infect Year: 2021 Document Type: Article Affiliation country: 22221751.2021.2008776

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