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Broad impacts of COVID-19 pandemic on acute respiratory infections in China: an observational study.
Li, Zhong-Jie; Yu, Lin-Jie; Zhang, Hai-Yang; Shan, Chun-Xi; Lu, Qing-Bin; Zhang, Xiao-Ai; Ren, Xiang; Zhang, Cui-Hong; Wang, Yi-Fei; Lin, Sheng-Hong; Xu, Qiang; Jiang, Bao-Gui; Jiang, Tao; Lv, Chen-Long; Chen, Jin-Jin; Gao, George F; Yang, Wei-Zhong; Wang, Li-Ping; Yang, Yang; Fang, Li-Qun; Liu, Wei.
  • Li ZJ; Division of Infectious Disease, Key Laboratory of Surveillance and Early-warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, China.
  • Yu LJ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.
  • Zhang HY; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.
  • Shan CX; Center for Disease Control and Prevention of Central Theater Command, Shijingshan District, Beijing, China.
  • Lu QB; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.
  • Zhang XA; Department of Laboratorial Science and Technology, School of Public Health, Peking University, Beijing, P. R. China.
  • Ren X; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.
  • Zhang CH; Division of Infectious Disease, Key Laboratory of Surveillance and Early-warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, China.
  • Wang YF; Division of Infectious Disease, Key Laboratory of Surveillance and Early-warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, China.
  • Lin SH; Division of Infectious Disease, Key Laboratory of Surveillance and Early-warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, China.
  • Xu Q; Division of Infectious Disease, Key Laboratory of Surveillance and Early-warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, China.
  • Jiang BG; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.
  • Jiang T; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.
  • Lv CL; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.
  • Chen JJ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.
  • Gao GF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.
  • Yang WZ; Chinese Center for Disease Control and Prevention, Beijing, China.
  • Wang LP; Chinese Center for Disease Control and Prevention, Beijing, China.
  • Yang Y; Division of Infectious Disease, Key Laboratory of Surveillance and Early-warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, China.
  • Fang LQ; Department of Biostatistics, College of Public Health and Health Professions, and Emerging Pathogens Institute, University of Florida, Gainesville, Florida, USA.
  • Liu W; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.
Clin Infect Dis ; 2021 Nov 12.
Article in English | MEDLINE | ID: covidwho-1522157
ABSTRACT

BACKGROUND:

To combat the COVID-19 pandemic, nonpharmaceutical interventions (NPI) were implemented worldwide, which impacted a broad spectrum of acute respiratory infections (ARI).

METHODS:

Etiologically diagnostic data from 142 559 cases with ARIs, who were tested for eight viral pathogens (influenza virus, IFV; respiratory syncytial virus, RSV; human parainfluenza virus, HPIV; human adenovirus; human metapneumovirus; human coronavirus, HCoV; human bocavirus, HBoV, and human rhinovirus, HRV) between 2012 and 2021, were analyzed to assess the changes of respiratory infections in China during the first COVID-19 pandemic year compared to pre-pandemic years.

RESULTS:

Test positive rates of all respiratory viruses decreased during 2020, compared to the average levels during 2012-2019, with changes ranging from -17·2% for RSV to -87·6% for IFV. Sharp decreases mostly occurred between February and August when massive NPIs remained active, although HRV rebounded to the historical level during the summer. While IFV and HMPV were consistently suppressed year round, RSV, HPIV, HCoV, HRV HBov resurged and went beyond historical levels during September, 2020-January, 2021, after NPIs were largely relaxed and schools reopened. Resurgence was more prominent among children younger than 18 years and in Northern China. These observations remain valid after accounting for seasonality and long-term trend of each virus.

CONCLUSIONS:

Activities of respiratory viral infections were reduced substantially in the early phases of the COVID-19 pandemic, and massive NPIs were likely the main driver. Lifting of NPIs can lead to resurgence of viral infections, particularly in children.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Language: English Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: Cid

Full text: Available Collection: International databases Database: MEDLINE Language: English Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: Cid