Neuroradiologic Imaging of Neurologic and Neuro-Ophthalmic Complications of Coronavirus-19 Infection.
J Neuroophthalmol
; 41(4): 452-460, 2021 12 01.
Article
in English
| MEDLINE | ID: covidwho-1522456
ABSTRACT
BACKGROUND:
To review the literature and provide a summary of COVID-19-related neurologic and neuro-ophthalmic complications.METHODS:
The currently available literature was reviewed on PubMed and Google Scholar using the following keywords for searches CNS, Neuro-Ophthalmology, COVID-19, SARS-CoV-2, coronavirus, optic neuritis, pseudotumor cerebri, Acute Disseminated Encephalomyelitis, posterior reversible encephalopathy syndrome (PRES), meningitis, encephalitis, acute necrotizing hemorrhagic encephalopathy, and Guillain-Barré and Miller Fisher syndromes.RESULTS:
Neuroradiologic findings of neurologic and neuro-ophthalmologic complications in relationship to COVID-19 infection were reviewed. Afferent visual pathway-related disorders with relevant imaging manifestations included fundus nodules on MRI, papilledema and pseudotumor cerebri syndrome, optic neuritis, Acute Disseminated Encephalomyelitis, vascular injury with thromboembolism and infarct, leukoencephalopathy, gray matter hypoxic injury, hemorrhage, infectious meningitis/encephalitis, acute necrotizing hemorrhagic encephalopathy, and PRES. Efferent visual pathway-related complications with relevant imaging manifestations were also reviewed, including orbital abnormalities, cranial neuropathy, Guillain-Barré and Miller Fisher syndromes, and nystagmus and other eye movement abnormalities related to rhombencephalitis.CONCLUSION:
COVID-19 can cause central and peripheral nervous system disease, including along both the afferent and efferent components of visual axis. Manifestations of disease and long-term sequela continue to be studied and described. Familiarity with the wide variety of neurologic, ophthalmic, and neuroradiologic presentations can promote prompt and appropriate treatment and continue building a framework to understand the underlying mechanism of disease.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Brain
/
Optic Neuritis
/
Papilledema
/
Eye
/
Neuroimaging
/
COVID-19
Type of study:
Reviews
Topics:
Long Covid
Limits:
Humans
Language:
English
Journal:
J Neuroophthalmol
Journal subject:
Neurology
/
Ophthalmology
Year:
2021
Document Type:
Article
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