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Application of nano-graphene oxide as nontoxic disinfectant against alpha and betacoronaviruses.
Chung, Hee-Chun; Nguyen, Van Giap; Kim, Cheong Ung; Do, Hai-Quynh; Park, Bong Kyun; Park, Yong Ho; Song, Dae-Sub; Kong, Aeri; Ryu, Jae-Chul; Kang, Kyung-Sun.
  • Chung HC; Department of Veterinary Medicine Virology Lab, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, GwanAk-Gu, Seoul, Korea.
  • Nguyen VG; Faculty of Veterinary Medicine, Department of Veterinary Microbiology and Infectious Diseases, Vietnam National University of Agriculture, Hanoi, Vietnam.
  • Kim CU; Department of Veterinary Microbiology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, Republic of Korea.
  • Do HQ; Department of Veterinary Medicine Virology Lab, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, GwanAk-Gu, Seoul, Korea.
  • Park BK; Institute of Genome Research, Vietnam Academy of Science and Technology, Hanoi, Vietnam.
  • Park YH; Department of Veterinary Medicine Virology Lab, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, GwanAk-Gu, Seoul, Korea.
  • Song DS; Department of Veterinary Microbiology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, Republic of Korea.
  • Kong A; Department of Pharmacy, College of Pharmacy, Korea University, Sejong, Republic of Korea.
  • Ryu JC; Department of Medical Science, University of California, Los Angeles, California, USA.
  • Kang KS; Adult Stem, Cell Research Center and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
Vet Med Sci ; 7(6): 2434-2439, 2021 11.
Article in English | MEDLINE | ID: covidwho-1525489
ABSTRACT
New viruses are continuously emerging and recently there have been many great concerns on severe acute respiratory syndrome coronavirus (SARS-CoV-2). Nanographene oxide (nanoGO) has received much attention and is widely investigated to be utilised in therapy for infectious diseases by viruses. Thus, antiviral activity of nanoGO was evaluated using the porcine epidemic diarrhoea virus (PEDV), bovine coronavirus (BCoV), and SARS-CoV-2, which are all Alpha- and Beta-coronavirus. In a virus inhibition assay, the three viruses were inhibited by nanoGO in a dose-dependent manner, including attempts in the presence of high serum solution which partially mimicked biological fluid.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Coronavirus / Nanostructures / Disinfectants / Graphite Type of study: Experimental Studies Limits: Humans Language: English Journal: Vet Med Sci Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Coronavirus / Nanostructures / Disinfectants / Graphite Type of study: Experimental Studies Limits: Humans Language: English Journal: Vet Med Sci Year: 2021 Document Type: Article