Your browser doesn't support javascript.
Guillain-Barré syndrome following the first dose of Pfizer-BioNTech COVID-19 vaccine: case report and review of reported cases.
Bouattour, Nadia; Hdiji, Olfa; Sakka, Salma; Fakhfakh, Emna; Moalla, Khadija; Daoud, Sawsan; Farhat, Nouha; Damak, Mariem; Mhiri, Chokri.
  • Bouattour N; Neurology's Department, Habib Bourguiba Hospital, Ferdaous Street, 3029, Sfax, Tunisia. bouattour_nadia@yahoo.fr.
  • Hdiji O; Laboratory of Neurogenetics, Parkinson's Disease and Cerebrovascular Disease (LR-12-SP-19), University of Sfax, Sfax, Tunisia. bouattour_nadia@yahoo.fr.
  • Sakka S; Neurology's Department, Habib Bourguiba Hospital, Ferdaous Street, 3029, Sfax, Tunisia.
  • Fakhfakh E; Laboratory of Neurogenetics, Parkinson's Disease and Cerebrovascular Disease (LR-12-SP-19), University of Sfax, Sfax, Tunisia.
  • Moalla K; Neurology's Department, Habib Bourguiba Hospital, Ferdaous Street, 3029, Sfax, Tunisia.
  • Daoud S; Laboratory of Neurogenetics, Parkinson's Disease and Cerebrovascular Disease (LR-12-SP-19), University of Sfax, Sfax, Tunisia.
  • Farhat N; Neurology's Department, Habib Bourguiba Hospital, Ferdaous Street, 3029, Sfax, Tunisia.
  • Damak M; Laboratory of Neurogenetics, Parkinson's Disease and Cerebrovascular Disease (LR-12-SP-19), University of Sfax, Sfax, Tunisia.
  • Mhiri C; Neurology's Department, Habib Bourguiba Hospital, Ferdaous Street, 3029, Sfax, Tunisia.
Neurol Sci ; 43(2): 755-761, 2022 Feb.
Article in English | MEDLINE | ID: covidwho-1525541
ABSTRACT

BACKGROUND:

Since the SARS-CoV-2 pandemic has started in December 2019, millions of people have been infected all over the world. Vaccination is the most efficient tool to end this pandemic, but vaccine surveillance is necessary to identify side effects. Some studies have shown that neurological complications after COVID-19 vaccination are rare and dominated by demyelinating disease. CASE PRESENTATION We present a case of a 67-year-old man who presented 7 days following his first dose of Pfizer-BioNTech COVID-19 vaccine a rapidly progressive ascending muscle weakness. The diagnosis of Guillain-Barré syndrome (GBS) was confirmed according to the clinical features, the albumino-cytological dissociation in the cerebrospinal fluid, and the electroneuromyography findings. The workup for all known infections associated with immune-mediated GBS was negative. The patient received treatment with intravenous immunoglobulin. Neurological examination 1 month after discharge showed full recovery and he regained his baseline functional status.

CONCLUSIONS:

As far as we know, this is the first reported case in Tunisia. Although extremely rare, neurologists should remain vigilant for acute inflammatory demyelinating polyradiculoneuropathy after COVID-19 vaccination.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Guillain-Barre Syndrome / COVID-19 Type of study: Case report / Prognostic study Topics: Vaccines Limits: Aged / Humans / Male Language: English Journal: Neurol Sci Journal subject: Neurology Year: 2022 Document Type: Article Affiliation country: S10072-021-05733-x

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Guillain-Barre Syndrome / COVID-19 Type of study: Case report / Prognostic study Topics: Vaccines Limits: Aged / Humans / Male Language: English Journal: Neurol Sci Journal subject: Neurology Year: 2022 Document Type: Article Affiliation country: S10072-021-05733-x