Overall Impact of Coronavirus Disease 2019 Outbreak in Children With Functional Abdominal Pain Disorders: Results From the First Pandemic Phase.
J Pediatr Gastroenterol Nutr
; 73(6): 689-694, 2021 12 01.
Article
in English
| MEDLINE | ID: covidwho-1612727
ABSTRACT
OBJECTIVE:
We aimed to assess how the first phase of coronavirus disease 2019 (COVID-19) pandemic influenced symptoms in children with functional abdominal pain disorders (FAPDs) and to characterize their quality of life (QoL), anxiety and global health.METHODS:
This was a multicenter, observational, international study conducted between April and July 2020 at six different referral centers. Children diagnosed with FAPDs between October 2019 and February 2020 were enrolled and prospectively interviewed at 4âmonths of follow-up during the first pandemic phase (Quarantine group). Patients were asked to complete PedsQL 4.0 Generic Core Scale and PROMIS Anxiety and Global Health questionnaires. A cohort of children diagnosed with FAPDs between October 2018 and February 2019 was used as a Control group.RESULTS:
Three-hundred-fifty-six children were enrolled of whom 180 (mean age at diagnosis 14â±â2.8âyears) in the Quarantine group and 176 (mean age at diagnosis 13â±â2.8âyears) in the Control group. At 4âmonths of follow-up, we observed a significant reduction of children reporting >5 episodes of abdominal pain per month when compared to baseline, in both groups (Quarantine group 63.9% vs 42.2%, Pâ<â0.001; Control group 83.5% vs 50%, Pâ<â0.001). The Quarantine group had median QoL values of 84.8 with 16.6% of children showing high anxiety values and 55% having decreased global health score.CONCLUSIONS:
We demonstrated symptoms' improvement at 4âmonths of follow-up in both cohorts. During the first months of the COVID-19 quarantine children with FAPDs showed satisfactory QoL and anxiety scores, suggesting positive effects of school closure and increased parental attention.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Quality of Life
/
COVID-19
Type of study:
Cohort study
/
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Child
/
Humans
Language:
English
Journal:
J Pediatr Gastroenterol Nutr
Year:
2021
Document Type:
Article
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