Factors associated with admission to the intensive care unit and mortality in patients with COVID-19, Colombia.
PLoS One
; 16(11): e0260169, 2021.
Article
in English
| MEDLINE | ID: covidwho-1526694
ABSTRACT
INTRODUCTION:
Coronavirus disease 2019 (COVID-19) has affected millions of people worldwide, and several sociodemographic variables, comorbidities and care variables have been associated with complications and mortality.OBJECTIVE:
To identify the factors associated with admission to intensive care units (ICUs) and mortality in patients with COVID-19 from 4 clinics in Colombia.METHODS:
This was a follow-up study of a cohort of patients diagnosed with COVID-19 between March and August 2020. Sociodemographic, clinical (Charlson comorbidity index and NEWS 2 score) and pharmacological variables were identified. Multivariate analyses were performed to identify variables associated with the risk of admission to the ICU and death (p<0.05).RESULTS:
A total of 780 patients were analyzed, with a median age of 57.0 years; 61.2% were male. On admission, 54.9% were classified as severely ill, 65.3% were diagnosed with acute respiratory distress syndrome, 32.4% were admitted to the ICU, and 26.0% died. The factors associated with a greater likelihood of ICU admission were severe pneumonia (OR 9.86; 95%CI5.99-16.23), each 1-point increase in the NEWS 2 score (OR1.09; 95%CI1.002-1.19), history of ischemic heart disease (OR3.24; 95%CI1.16-9.00), and chronic obstructive pulmonary disease (OR2.07; 95%CI1.09-3.90). The risk of dying increased in those older than 65 years (OR3.08; 95%CI1.66-5.71), in patients with acute renal failure (OR6.96; 95%CI4.41-11.78), admitted to the ICU (OR6.31; 95%CI3.63-10.95), and for each 1-point increase in the Charlson comorbidity index (OR1.16; 95%CI1.002-1.35).CONCLUSIONS:
Factors related to increasing the probability of requiring ICU care or dying in patients with COVID-19 were identified, facilitating the development of anticipatory intervention measures that favor comprehensive care and improve patient prognosis.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Patient Admission
/
Hospital Mortality
/
COVID-19
/
Intensive Care Units
Type of study:
Cohort study
/
Observational study
/
Prognostic study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
South America
/
Colombia
Language:
English
Journal:
PLoS One
Journal subject:
Science
/
Medicine
Year:
2021
Document Type:
Article
Affiliation country:
Journal.pone.0260169
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