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TransCOVID: Does Gender-Affirming Hormone Therapy Play a Role in Contracting COVID-19?
Durcan, Emre; Turan, Senol; Bircan, Basak Ecem; Yaylamaz, Selver; Demirel, Oznur; Demir, Ahmet Numan; Sulu, Cem; Kara, Zehra; Sahin, Serdar; Taze, Sabriye Sibel; Mefkure Ozkaya, Hande; Kadioglu, Pinar.
  • Durcan E; Division of Endocrinology and Metabolism, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.
  • Turan S; Department of Psychiatry, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.
  • Bircan BE; Division of Endocrinology and Metabolism, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.
  • Yaylamaz S; Division of Endocrinology and Metabolism, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.
  • Demirel O; Department of Psychiatry, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.
  • Demir AN; Division of Endocrinology and Metabolism, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.
  • Sulu C; Division of Endocrinology and Metabolism, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.
  • Kara Z; Division of Endocrinology and Metabolism, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.
  • Sahin S; Division of Endocrinology and Metabolism, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.
  • Taze SS; Division of Endocrinology and Metabolism, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.
  • Mefkure Ozkaya H; Division of Endocrinology and Metabolism, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.
  • Kadioglu P; Division of Endocrinology and Metabolism, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.
J Sex Marital Ther ; 48(4): 415-426, 2022.
Article in English | MEDLINE | ID: covidwho-1528058
ABSTRACT
Based on the possible effects of androgens on the course of COVID-19, it can be posited that Gender-Affirming Hormone Therapy (GAHT) may affect the course of the disease in people with GD. We aimed to investigate the relationship between GAHT and contracting COVID-19, as well as the severity of the disease in individuals with Gender Dysphoria (GD). The single center, cross-sectional, web-based survey was completed by people with GD who received GAHT. The questionnaire contained three parts a sociodemographic data form; a GAHT data form; a COVID-19-related data form. Of the 238 participants, 179 were individuals with female-to-male (FtM) and 59 male-to-female (MtF) GD. We detected that the risk of contracting COVID-19 increased 3.46 times in people with FtM GD, who had received testosterone therapy, in comparison to people with MtF GD, who received estrogen and anti-androgen therapy. Additionally, people with FtM GD who contracted COVID-19 had received longer testosterone therapy when compared to those who did not contract COVID-19. Our findings indicate that individuals with FtM GD who receive testosterone treatment within the scope of GAHT are at higher risk of contracting COVID-19 and that the clinicians who follow-up on GAHT should be more careful about this issue.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Transgender Persons / Gender Dysphoria / COVID-19 / COVID-19 Drug Treatment Type of study: Cohort study / Observational study / Prognostic study / Randomized controlled trials Limits: Female / Humans / Male Language: English Journal: J Sex Marital Ther Year: 2022 Document Type: Article Affiliation country: 0092623X.2021.2000535

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Transgender Persons / Gender Dysphoria / COVID-19 / COVID-19 Drug Treatment Type of study: Cohort study / Observational study / Prognostic study / Randomized controlled trials Limits: Female / Humans / Male Language: English Journal: J Sex Marital Ther Year: 2022 Document Type: Article Affiliation country: 0092623X.2021.2000535