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Prevalence of Persistent Olfactory Disorders in Patients With COVID-19: A Psychophysical Case-Control Study With 1-Year Follow-up.
Vaira, Luigi Angelo; Salzano, Giovanni; Le Bon, Serge Daniel; Maglio, Angelantonio; Petrocelli, Marzia; Steffens, Younes; Ligas, Enrica; Maglitto, Fabio; Lechien, Jerome R; Saussez, Sven; Vatrella, Alessandro; Salzano, Francesco Antonio; Boscolo-Rizzo, Paolo; Hopkins, Claire; De Riu, Giacomo.
  • Vaira LA; Maxillofacial Surgery Operative Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.
  • Salzano G; Biomedical Science PhD School, Biomedical Science Department, University of Sassari, Sassari, Italy.
  • Le Bon SD; Maxillofacial Surgery Operative Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.
  • Maglio A; Maxillofacial Surgery Unit, University Hospital of Naples Federico II, Naples, Italy.
  • Petrocelli M; Department of Otorhinolaryngology and Head and Neck Surgery, CHU de Bruxelles, CHU Saint-Pierre, School of Medicine, Université Libre de Bruxelles, Brussels, Belgium.
  • Steffens Y; Respiratory Diseases Operative Unit, Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, Baronissi, Italy.
  • Ligas E; Maxillofacial Surgery Operative Unit, Bellaria and Maggiore Hospital-AUSL of Bologna, Bologna, Italy.
  • Maglitto F; Department of Otorhinolaryngology and Head and Neck Surgery, CHU de Bruxelles, CHU Saint-Pierre, School of Medicine, Université Libre de Bruxelles, Brussels, Belgium.
  • Lechien JR; Maxillofacial Surgery Operative Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.
  • Saussez S; Maxillofacial Surgery Operative Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.
  • Vatrella A; Maxillofacial Surgery Unit, University Hospital of Naples Federico II, Naples, Italy.
  • Salzano FA; Department of Otolaryngology-Head Neck Surgery, Foch Hospital, Paris Saclay University, Paris, France.
  • Boscolo-Rizzo P; Department of Human and Experimental Oncology, Faculty of Medicine UMONS Research Institute for Health Sciences and Technology, University of Mons, Mons, Belgium.
  • Hopkins C; Department of Human and Experimental Oncology, Faculty of Medicine UMONS Research Institute for Health Sciences and Technology, University of Mons, Mons, Belgium.
  • De Riu G; Respiratory Diseases Operative Unit, Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, Baronissi, Italy.
Otolaryngol Head Neck Surg ; 167(1): 183-186, 2022 07.
Article in English | MEDLINE | ID: covidwho-1528640
ABSTRACT
The purpose of this multicenter case-control study was to evaluate a group of patients at least 1 year after coronavirus disease 2019 (COVID-19) with Sniffin' Sticks tests and to compare the results with a control population to quantify the potential bias introduced by the underlying prevalence of olfactory dysfunction (OD) in the general population. The study included 170 cases and 170 controls. In the COVID-19 group, 26.5% of cases had OD (anosmia in 4.7%, hyposmia in 21.8%) versus 3.5% in the control group (6 cases of hyposmia). The TDI score (threshold, discrimination, and identification) in the COVID-19 group was significantly lower than in the control group (32.5 [interquartile range, 29-36.5] vs 36.75 [34-39.5], P < .001). The prevalence of OD was significantly higher in the COVID-19 group, confirming that this result is not due to the underlying prevalence of OD in the general population.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Olfaction Disorders Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Limits: Humans Language: English Journal: Otolaryngol Head Neck Surg Journal subject: Otolaryngology Year: 2022 Document Type: Article Affiliation country: 01945998211061511

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Olfaction Disorders Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Limits: Humans Language: English Journal: Otolaryngol Head Neck Surg Journal subject: Otolaryngology Year: 2022 Document Type: Article Affiliation country: 01945998211061511