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Modelling aerosol-based exposure to SARS-CoV-2 by an agent based Monte Carlo method: Risk estimates in a shop and bar.
Salmenjoki, Henri; Korhonen, Marko; Puisto, Antti; Vuorinen, Ville; Alava, Mikko J.
  • Salmenjoki H; Department of Applied Physics, Aalto University, Espoo, Finland.
  • Korhonen M; Department of Mechanical Engineering, Aalto University, Espoo, Finland.
  • Puisto A; Department of Applied Physics, Aalto University, Espoo, Finland.
  • Vuorinen V; Department of Mechanical Engineering, Aalto University, Espoo, Finland.
  • Alava MJ; Department of Applied Physics, Aalto University, Espoo, Finland.
PLoS One ; 16(11): e0260237, 2021.
Article in English | MEDLINE | ID: covidwho-1528725
ABSTRACT
Present day risk assessment on the spreading of airborne viruses is often based on the classical Wells-Riley model assuming immediate mixing of the aerosol into the studied environment. Here, we improve on this approach and the underlying assumptions by modeling the space-time dependency of the aerosol concentration via a transport equation with a dynamic source term introduced by the infected individual(s). In the present agent-based methodology, we study the viral aerosol inhalation exposure risk in two scenarios including a low/high risk scenario of a "supermarket"/"bar". The model takes into account typical behavioral patterns for determining the rules of motion for the agents. We solve a diffusion model for aerosol concentration in the prescribed environments in order to account for local exposure to aerosol inhalation. We assess the infection risk using the Wells-Riley model formula using a space-time dependent aerosol concentration. The results are compared against the classical Wells-Riley model. The results indicate features that explain individual cases of high risk with repeated sampling of a heterogeneous environment occupied by non-equilibrium concentration clouds. An example is the relative frequency of cases that might be called superspreading events depending on the model parameters. A simple interpretation is that averages of infection risk are often misleading. They also point out and explain the qualitative and quantitative difference between the two cases-shopping is typically safer for a single individual person.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Social Behavior / Basic Reproduction Number / COVID-19 Type of study: Prognostic study / Qualitative research Limits: Humans Language: English Journal: PLoS One Journal subject: Science / Medicine Year: 2021 Document Type: Article Affiliation country: Journal.pone.0260237

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Social Behavior / Basic Reproduction Number / COVID-19 Type of study: Prognostic study / Qualitative research Limits: Humans Language: English Journal: PLoS One Journal subject: Science / Medicine Year: 2021 Document Type: Article Affiliation country: Journal.pone.0260237