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Proposed Pathogenesis, Characteristics, and Management of COVID-19 mRNA Vaccine-Related Myopericarditis.
Hajra, Adrija; Gupta, Manasvi; Ghosh, Binita; Ashish, Kumar; Patel, Neelkumar; Manek, Gaurav; Rai, Devesh; Sreenivasan, Jayakumar; Goel, Akshay; Lavie, Carl J; Bandyopadhyay, Dhrubajyoti.
  • Hajra A; Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA. adrija847@gmail.com.
  • Gupta M; University of Connecticut, Farmington, CT, USA.
  • Ghosh B; Burdwan Medical College, Burdwan, West Bengal, India.
  • Ashish K; Crozer-Chester Medical Center, Upland, PA, 19013, USA.
  • Patel N; University of Kansas, Kansas City, KS, USA.
  • Manek G; Department of Internal Medicine, University of Connecticut, Farmington, CT, USA.
  • Rai D; Rochester General Hospital, Rochester, NY, USA.
  • Sreenivasan J; New York Medical College at Westchester Medical Center, New York, NY, USA.
  • Goel A; New York Medical College at Westchester Medical Center, New York, NY, USA.
  • Lavie CJ; John Ochsner Heart and Vascular Institute, Ochsner Clinical School-the University of Queensland School of Medicine, New Orleans, LA, USA.
  • Bandyopadhyay D; New York Medical College at Westchester Medical Center, New York, NY, USA.
Am J Cardiovasc Drugs ; 22(1): 9-26, 2022 Jan.
Article in English | MEDLINE | ID: covidwho-1530485
ABSTRACT
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the novel coronavirus causing coronavirus disease 2019 (COVID-19), has affected human lives across the globe. On 11 December 2020, the US FDA granted an emergency use authorization for the first COVID-19 vaccine, and vaccines are now widely available. Undoubtedly, the emergence of these vaccines has led to substantial relief, helping alleviate the fear and anxiety around the COVID-19 illness for both the general public and clinicians. However, recent cases of vaccine complications, including myopericarditis, have been reported after administration of COVID-19 vaccines. This article discusses the cases, possible pathogenesis of myopericarditis, and treatment of the condition. Most cases were mild and should not yet change vaccine policies, although prospective studies are needed to better assess the risk-benefit ratios in different groups.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / Myocarditis Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Humans Language: English Journal: Am J Cardiovasc Drugs Journal subject: Vascular Diseases / Cardiology / Drug Therapy Year: 2022 Document Type: Article Affiliation country: S40256-021-00511-8

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / Myocarditis Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Humans Language: English Journal: Am J Cardiovasc Drugs Journal subject: Vascular Diseases / Cardiology / Drug Therapy Year: 2022 Document Type: Article Affiliation country: S40256-021-00511-8