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A Brazilian multicenter pilot case series on the efficacy of photobiomodulation therapy for COVID-19-related taste dysfunction.
Campos, Luana; Soares, Luís Eduardo Silva; Berlingieri, Giuseppina; Ramires, Marcia Christina Camargo Hernandes; Guirado, Milena Miranda Goulart; Lyra, Luciana Aparecida de Oliveira P; Teixeira, Inessa Solek; Oliveira, Patrícia Costa; Alvares, Cristina Maria Arvate; Palma, Luiz Felipe.
  • Campos L; Graduate Program in Implantology, University of Santo Amaro, School of Dentistry. São Paulo, SP, Brazil; Study Group of Laser and Health Institute. São Paulo, SP, Brazil.
  • Soares LES; Study Group of Laser and Health Institute. São Paulo, SP, Brazil; Graduate Program in Biomedical Engineering, University of Vale do Paraíba, Research and Development Institute. São José dos Campos, SP, Brazil.
  • Berlingieri G; Study Group of Laser and Health Institute. São Paulo, SP, Brazil.
  • Ramires MCCH; Study Group of Laser and Health Institute. São Paulo, SP, Brazil; Doutor José de Carvalho Florence Hospital. São José dos Campos, SP, Brazil.
  • Guirado MMG; Study Group of Laser and Health Institute. São Paulo, SP, Brazil; Doutor José de Carvalho Florence Hospital. São José dos Campos, SP, Brazil.
  • Lyra LAOP; Study Group of Laser and Health Institute. São Paulo, SP, Brazil; Scholl of Health Science, Universidade Positivo. Curitiba, PR, Brazil.
  • Teixeira IS; Study Group of Laser and Health Institute. São Paulo, SP, Brazil; Imperial Charity Hospital. Florianópolis, SC, Brazil.
  • Oliveira PC; Study Group of Laser and Health Institute. São Paulo, SP, Brazil; Instituto Federal do Paraná, Campus Londrina. Londrina, PR, Brazil.
  • Alvares CMA; Graduate Program in Implantology, University of Santo Amaro, School of Dentistry. São Paulo, SP, Brazil.
  • Palma LF; Graduate Dentistry Program, Ibirapuera University. São Paulo, SP, Brazil. Electronic address: luizfelipep@hotmail.com.
Photodiagnosis Photodyn Ther ; 37: 102643, 2022 Mar.
Article in English | MEDLINE | ID: covidwho-1531705
ABSTRACT
BACKGROUND AND

AIM:

Among the most common symptoms of COVID-19 is taste dysfunction, which has a ranging clinical presentation. As well as its pathophysiology remains to be unclear, there is not enough information about the efficacy and safety of the available treatments. This study aims to report a series of cases using PBMT for the management of COVID-19-related taste impairment. CASE SERIES 8 female and 2 male patients sought medical help for taste impairment (either partially or completely) after COVID-19 infection. Photobiomodulation therapy (PBMT) on the tongue mucosa was then proposed but with 3 different protocols. Taste perception at baseline and before every laser session was evaluated using a visual analog scale. Irrespective of the PBMT protocol, taste recovery was noted in all cases but with varying degrees of improvement.

CONCLUSION:

given the high prevalence rates of taste dysfunction in COVID-19 patients and the lack of information about the available treatments, PBMT seems to be a promising therapeutic modality but not dependent on the total number of laser sessions and the interval between them. The choice of the most suitable laser protocol as well as the knowledge of the exact photonic mechanisms, however, need to be better studied.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Photochemotherapy / Low-Level Light Therapy / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Limits: Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Photodiagnosis Photodyn Ther Journal subject: Diagnostic Imaging / Therapeutics Year: 2022 Document Type: Article Affiliation country: J.pdpdt.2021.102643

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Photochemotherapy / Low-Level Light Therapy / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Limits: Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Photodiagnosis Photodyn Ther Journal subject: Diagnostic Imaging / Therapeutics Year: 2022 Document Type: Article Affiliation country: J.pdpdt.2021.102643