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Are COVID-19 Vaccine Boosters Needed? The Science behind Boosters.
Burckhardt, Rachel M; Dennehy, John J; Poon, Leo L M; Saif, Linda J; Enquist, Lynn W.
  • Burckhardt RM; American Academy of Microbiology, Washington, DC, USA.
  • Dennehy JJ; Biology Department, Queens College and The Graduate Center of The City University of New York, New York, New York, USA.
  • Poon LLM; School of Public Health & HKU-Pasteur Research Pole, LKS Faculty of Medicine, The University of Hong Konggrid.194645.b, Hong Kong, China.
  • Saif LJ; Center for Food Animal Health, Department of Animal Sciences, College of Food, Agricultural and Environmental Sciences, OARDC, The Ohio State Universitygrid.261331.4, Wooster, Ohio, USA.
  • Enquist LW; Veterinary Preventive Medicine Department, College of Veterinary Medicine, The Ohio State Universitygrid.261331.4, Wooster, Ohio, USA.
J Virol ; 96(3): e0197321, 2022 Feb 09.
Article in English | MEDLINE | ID: covidwho-1532966
ABSTRACT
Waning vaccine-induced immunity coupled with the emergence of SARS-CoV-2 variants has led to increases in breakthrough infections, prompting consideration for vaccine booster doses. Boosters have been reported to be safe and increase SARS-CoV-2-specific neutralizing antibody levels, but how these doses impact the trajectory of the global pandemic and herd immunity is unknown. Information on immunology, epidemiology, and equitable vaccine distribution should be considered when deciding the timing and eligibility for COVID-19 vaccine boosters.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Immunization, Secondary / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 / Health Services Needs and Demand Type of study: Observational study / Prognostic study Topics: Vaccines / Variants Limits: Humans Language: English Journal: J Virol Year: 2022 Document Type: Article Affiliation country: JVI.01973-21

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Immunization, Secondary / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 / Health Services Needs and Demand Type of study: Observational study / Prognostic study Topics: Vaccines / Variants Limits: Humans Language: English Journal: J Virol Year: 2022 Document Type: Article Affiliation country: JVI.01973-21