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Leg paralysis after AstraZeneca COVID-19 vaccination diagnosed as neuralgic amyotrophy of the lumbosacral plexus: a case report.
Kim, Se Il; Seok, Hung Youl; Yi, Jaehyuck; Cho, Jang Hyuk.
  • Kim SI; Department of Rehabilitation Medicine, 37976Keimyung University School of Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Republic of Korea.
  • Seok HY; Department of Neurology, 37976Keimyung University School of Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Republic of Korea.
  • Yi J; Department of Radiology, 37976Keimyung University School of Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Republic of Korea.
  • Cho JH; Department of Rehabilitation Medicine, 37976Keimyung University School of Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Republic of Korea.
J Int Med Res ; 49(11): 3000605211056783, 2021 Nov.
Article in English | MEDLINE | ID: covidwho-1533180
ABSTRACT
The ongoing global administration of vaccines for coronavirus disease 2019 (COVID-19) means that increasing numbers of patients are likely to present with post-vaccination complications. We describe the first reported case of neuralgic amyotrophy (NA) involving the lumbosacral plexus occurring after AstraZeneca COVID-19 vaccination. The patient presented with acute-onset leg paralysis following administration of the vaccine. Based on the clinical, electrodiagnostic, and radiologic findings, the patient was diagnosed with post-vaccination NA. We speculate that the COVID-19 vaccine elicited an immune-mediated inflammatory response to the injected antigen due to inflammatory immunity in a patient with predisposed susceptibility to NA.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Brachial Plexus Neuritis / COVID-19 Type of study: Diagnostic study Limits: Humans Language: English Journal: J Int Med Res Year: 2021 Document Type: Article

Full text: Available Collection: International databases Database: MEDLINE Main subject: Brachial Plexus Neuritis / COVID-19 Type of study: Diagnostic study Limits: Humans Language: English Journal: J Int Med Res Year: 2021 Document Type: Article