Your browser doesn't support javascript.
Cognitive consequences of COVID-19: results of a cohort study from South America.
Crivelli, Lucía; Calandri, Ismael; Corvalán, Nicolás; Carello, María Agostina; Keller, Greta; Martínez, Carlos; Arruabarrena, Micaela; Allegri, Ricardo.
  • Crivelli L; Fleni, Department of Cognitive Neurology, Buenos Aires, Argentina.
  • Calandri I; Fleni, Department of Cognitive Neurology, Buenos Aires, Argentina.
  • Corvalán N; Fleni, Department of Cognitive Neurology, Buenos Aires, Argentina.
  • Carello MA; Fleni, Department of Cognitive Neurology, Buenos Aires, Argentina.
  • Keller G; Fleni, Department of Cognitive Neurology, Buenos Aires, Argentina.
  • Martínez C; Fleni, Department of Cognitive Neurology, Buenos Aires, Argentina.
  • Arruabarrena M; Fleni, Department of Cognitive Neurology, Buenos Aires, Argentina.
  • Allegri R; Fleni, Department of Cognitive Neurology, Buenos Aires, Argentina.
Arq Neuropsiquiatr ; 80(3): 240-247, 2022 03.
Article in English | MEDLINE | ID: covidwho-2293726
ABSTRACT

BACKGROUND:

Neurological and psychiatric manifestations associated with SARS-CoV-2 infection have been reported throughout the scientific literature. However, studies on post-COVID cognitive impairment in people with no previous cognitive complaint are scarce.

OBJECTIVE:

We aim to investigate the impact of COVID-19 on cognitive functions in adults without cognitive complaints before infection and to study cognitive dysfunction according to disease severity and cognitive risk factors.

METHODS:

Forty-five post-COVID-19 patients and forty-five controls underwent extensive neuropsychological evaluation, which assessed cognitive domains such as memory, language, attention, executive functions, and visuospatial skills, including psychiatric symptomatology scales. Data were collected on the severity of infection, premorbid medical conditions, and functionality for activities of daily living before and after COVID-19.

RESULTS:

Significant differences between groups were found in cognitive composites of memory (p=0.016, Cohen's d= 0.73), attention (p<0.001, Cohen's d=1.2), executive functions (p<0.001, Cohen's d=1.4), and language (p=0.002, Cohen's d=0.87). The change from premorbid to post-infection functioning was significantly different between severity groups (WHODAS, p=0.037). Self-reported anxiety was associated with the presence of cognitive dysfunction in COVID-19 subjects (p=0.043).

CONCLUSION:

Our results suggest that the presence of cognitive symptoms in post-COVID-19 patients may persist for months after disease remission and argue for the inclusion of cognitive assessment as a protocolized stage of the post-COVID examination. Screening measures may not be sufficient to detect cognitive dysfunction in post-COVID-19 patients.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Cognitive Dysfunction / COVID-19 Type of study: Cohort study / Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Adult / Humans Language: English Journal: Arq Neuropsiquiatr Year: 2022 Document Type: Article Affiliation country: 0004-282x-anp-2021-0320

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Cognitive Dysfunction / COVID-19 Type of study: Cohort study / Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Adult / Humans Language: English Journal: Arq Neuropsiquiatr Year: 2022 Document Type: Article Affiliation country: 0004-282x-anp-2021-0320