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COVID-19 associated symmetrical peripheral gangrene: A case series.
Sil, Abheek; Chakraborty, Uddalak; Chandra, Atanu; Biswas, Surajit Kumar.
  • Sil A; Department of Dermatology, Venereology, and Leprosy, RG Kar Medical College and Hospital, 1, Khudiram Bose Sarani, Kolkata, 700004, India.
  • Chakraborty U; Department of Neurology, Bangur Institute of Neurosciences, IPGMER and SSKM Hospital, Annex 1, 52/1 Shambhunath Pandit Street, Kolkata, 700020, India.
  • Chandra A; Department of Internal Medicine, RG Kar Medical College and Hospital, 1, Khudiram Bose Sarani, Kolkata, 700004, India. Electronic address: chandraatanu123@gmail.com.
  • Biswas SK; Department of Dermatology, Venereology, and Leprosy, RG Kar Medical College and Hospital, 1, Khudiram Bose Sarani, Kolkata, 700004, India.
Diabetes Metab Syndr ; 16(1): 102356, 2022 Jan.
Article in English | MEDLINE | ID: covidwho-1536514
ABSTRACT
BACKGROUND AND

AIMS:

The novel coronavirus disease (COVID-19) caused by SARS-CoV-2 has turned the world topsy-turvy since its onset in 2019. The thromboinflammatory complications of this disease are common in critically ill patients and associated with poor prognosis. Symmetrical peripheral gangrene (SPG) is characterized by symmetrical distal gangrene in absence of any large vessel occlusion or vasculitis and it is usually associated with critical illness. Our aim was to report the clinical profile and outcome of patients diagnosed with SPG associated with COVID-19. To the best of our knowledge, no such similar cases have been reported till date.

METHODS:

In this case series, we have discussed the clinical presentation, laboratory parameters and outcome in a series of two patients of SPG associated with COVID-19 and also compared those findings. Due to paucity of data, we also reviewed the literature on this under-diagnosed and rarely reported condition and association.

RESULTS:

Two consecutive patients (both males, age range 37-42 years, mean 39.5 years) were admitted with the diagnosis of COVID-19 associated SPG. Both patients had clinical and laboratory evidence of disseminated intravascular coagulation (DIC). Leucopenia was noted in both patients. Despite vigorous therapy, both patients succumbed to their illness within a fortnight of admission.

CONCLUSION:

SPG in the background of COVID-19 portends a fatal outcome. Physicians should be aware of its grim prognosis.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Gangrene / COVID-19 Type of study: Case report / Diagnostic study / Prognostic study Topics: Long Covid Limits: Adult / Humans / Male Country/Region as subject: Asia Language: English Journal: Diabetes Metab Syndr Year: 2022 Document Type: Article Affiliation country: J.dsx.2021.102356

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Gangrene / COVID-19 Type of study: Case report / Diagnostic study / Prognostic study Topics: Long Covid Limits: Adult / Humans / Male Country/Region as subject: Asia Language: English Journal: Diabetes Metab Syndr Year: 2022 Document Type: Article Affiliation country: J.dsx.2021.102356