Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is likely to be androgen mediated.

Wambier, Carlos Gustavo; Goren, Andy

Wambier, Carlos Gustavo; Goren, Andy.

Wambier CG; Department of Dermatology, The Warren Alpert Medical School of Brown University, Providence, Rhode Island. Electronic address: carlos_wambier@brown.edu.
Goren A; Applied Biology, Inc, Irvine, California.

J Am Acad Dermatol ; 83(1): 308-309, 2020 Jul.

Article in English | MEDLINE | ID: covidwho-153665

Subject(s)

Androgens/metabolism; Betacoronavirus/pathogenicity; Coronavirus Infections/pathology; Pneumonia, Viral/pathology; Spike Glycoprotein, Coronavirus/metabolism; Virus Internalization; Angiotensin-Converting Enzyme 2; Betacoronavirus/metabolism; COVID-19; Chromosomes, Human, X/genetics; Coronavirus Infections/epidemiology; Coronavirus Infections/virology; Genetic Loci; Humans; Pandemics; Peptidyl-Dipeptidase A/genetics; Peptidyl-Dipeptidase A/metabolism; Pneumonia, Viral/epidemiology; Pneumonia, Viral/virology; Promoter Regions, Genetic/genetics; Receptors, Androgen/genetics; Receptors, Androgen/metabolism; SARS-CoV-2; Serine Endopeptidases/genetics; Serine Endopeptidases/metabolism; Sex Factors; Transcription, Genetic; Viral Load

Keywords

5-α reductase; ACE2; COVID-19; SARS-CoV-2; TMPRSS2; androgen receptor; androgenetic alopecia; angiotensin converting enzyme 2; antiandrogen therapy; dutasteride; finasteride; human skin; retinoids; transmembrane protease serine 2

Fulltext

XML

PubMed Links

Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Virus Internalization / Spike Glycoprotein, Coronavirus / Betacoronavirus / Androgens Type of study: Observational study Limits: Humans Language: English Journal: J Am Acad Dermatol Year: 2020 Document Type: Article

Similar

MEDLINE

LILACS

LIS

Fulltext

XML

PubMed Links

Search on Google