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Non-pharmaceutical interventions and inoculation rate shape SARS-CoV-2 vaccination campaign success
Epidemiology and Infection ; 149:8, 2021.
Article in English | Web of Science | ID: covidwho-1537260
ABSTRACT
Nearly 1 year into the coronavirus disease 2019 pandemic, the first severe acute respiratory syndrome coronavirus 2 vaccines received emergency use authorisation and vaccination campaigns began. A number of factors can reduce the averted burden of cases and deaths due to vaccination. Here, we use a dynamic model, parametrised with Bayesian inference methods, to assess the effects of non-pharmaceutical interventions (NPIs) (such as social distancing, mask mandates, school and workplace closure), and vaccine administration and uptake rates on infections and deaths averted in the United States. We show that scenarios depicting higher compliance with NPIs avert more than 60% of infections and 70% of deaths during the period of vaccine administration, and that increasing the vaccination rate from 5 to 11 million people per week could increase the averted burden by more than one-third. These findings underscore the importance of maintaining NPIs and increasing vaccine administration rates.

Full text: Available Collection: Databases of international organizations Database: Web of Science Type of study: Experimental Studies Topics: Vaccines Language: English Journal: Epidemiology and Infection Year: 2021 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: Web of Science Type of study: Experimental Studies Topics: Vaccines Language: English Journal: Epidemiology and Infection Year: 2021 Document Type: Article