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COVID-19 patients with increasing age experience differential time to initial medical care and severity of symptoms.
Mancilla-Galindo, J; Kammar-García, A; Martínez-Esteban, A; Meza-Comparán, H D; Mancilla-Ramírez, J; Galindo-Sevilla, N.
  • Mancilla-Galindo J; Unidad de Investigación UNAM-INC, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
  • Kammar-García A; Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City, Mexico.
  • Martínez-Esteban A; Dirección de Investigación, Instituto Nacional de Geriatría, Mexico City, Mexico.
  • Meza-Comparán HD; Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
  • Mancilla-Ramírez J; Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
  • Galindo-Sevilla N; Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City, Mexico.
Epidemiol Infect ; 149: e230, 2021 10 22.
Article in English | MEDLINE | ID: covidwho-1537261
ABSTRACT
We conducted a retrospective observational study in patients with laboratory-confirmed coronavirus disease (COVID-19) who received medical care in 688 COVID-19 ambulatory units and hospitals in Mexico City between 24 February 2020 and 24 December 2020, to study if the elderly seek medical care later than younger patients and their severity of symptoms at initial medical evaluation. Patients were categorised into eight groups (<20, 20-29, 30-39, 40-49, 50-59, 60-69, 70-79 and ≥80 years). Symptoms at initial evaluation were classified according to a previously validated classification into respiratory and non-respiratory symptoms. Comparisons between time from symptom onset to medical care for every age category were performed through variance analyses. Logistic regression models were applied to determine the risk of presenting symptoms of severity according to age, and mortality risk according to delays in medical care. In total, 286 020 patients were included (mean age 42.8, s.d. 16.8 years; 50.4% were women). Mean time from symptom onset to medical care was 4.04 (s.d. 3.6) days and increased with older age categories (P < 0.0001). Mortality risk increased by 6.4% for each day of delay in medical care from symptom onset. The risk of presenting with the symptoms of severity was greater with increasing age categories. In conclusion, COVID-19 patients with increasing ages tend to seek medical care later, with higher rates of symptoms of severity at initial presentation in both ambulatory units and hospitals.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Aging / Time-to-Treatment / COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Country/Region as subject: Mexico Language: English Journal: Epidemiol Infect Journal subject: Communicable Diseases / Epidemiology Year: 2021 Document Type: Article Affiliation country: S095026882100234x

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Aging / Time-to-Treatment / COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Country/Region as subject: Mexico Language: English Journal: Epidemiol Infect Journal subject: Communicable Diseases / Epidemiology Year: 2021 Document Type: Article Affiliation country: S095026882100234x