Your browser doesn't support javascript.
Comprehensive and long-term surveys of COVID-19 sequelae in Japan, an ambidirectional multicentre cohort study: study protocol.
Nakagawara, Kensuke; Namkoong, Ho; Terai, Hideki; Masaki, Katsunori; Tanosaki, Takae; Shimamoto, Kyoko; Lee, Ho; Tanaka, Hiromu; Okamori, Satoshi; Kabata, Hiroki; Chubachi, Shotaro; Ikemura, Shinnosuke; Kamata, Hirofumi; Yasuda, Hiroyuki; Kawada, Ichiro; Ishii, Makoto; Ishibashi, Yoshiki; Harada, Sei; Fujita, Takanori; Ito, Daisuke; Bun, Shogyoku; Tabuchi, Hajime; Kanzaki, Sho; Shimizu, Eisuke; Fukuda, Keitaro; Yamagami, Jun; Kobayashi, Keigo; Hirano, Toshiyuki; Inoue, Takashi; Kagyo, Junko; Shiomi, Tetsuya; Ohgino, Keiko; Sayama, Koichi; Otsuka, Kengo; Miyao, Naoki; Odani, Toshio; Oyamada, Yoshitaka; Masuzawa, Keita; Nakayama, Sohei; Suzuki, Yusuke; Baba, Rie; Nakachi, Ichiro; Kuwahara, Naota; Ishiguro, Takashi; Mashimo, Shuko; Minematsu, Naoto; Ueda, Soichiro; Manabe, Tadashi; Funatsu, Yohei; Koh, Hidefumi.
  • Nakagawara K; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Namkoong H; Department of Infectious Diseases, Keio University School of Medicine, Tokyo, Japan hounamugun@gmail.com.
  • Terai H; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Masaki K; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Tanosaki T; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Shimamoto K; Keio Global Research Institute, Keio University, Tokyo, Japan.
  • Lee H; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Tanaka H; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Okamori S; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Kabata H; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Chubachi S; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Ikemura S; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Kamata H; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Yasuda H; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Kawada I; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Ishii M; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Ishibashi Y; Department of Preventive Medicine and Public Health, Keio University School of Medicine, Tokyo, Japan.
  • Harada S; Department of Preventive Medicine and Public Health, Keio University School of Medicine, Tokyo, Japan.
  • Fujita T; Department of Health Policy and Management, Keio University School of Medicine, Tokyo, Japan.
  • Ito D; Department of Neurology, Keio University School of Medicine, Tokyo, Japan.
  • Bun S; Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
  • Tabuchi H; Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
  • Kanzaki S; Department of Otolaryngology, Keio University School of Medicine, Tokyo, Japan.
  • Shimizu E; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
  • Fukuda K; Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.
  • Yamagami J; Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.
  • Kobayashi K; Department of Internal Medicine, Sano Kosei General Hospital, Tochigi, Japan.
  • Hirano T; Department of Internal Medicine, Sano Kosei General Hospital, Tochigi, Japan.
  • Inoue T; Department of Internal Medicine, Sano Kosei General Hospital, Tochigi, Japan.
  • Kagyo J; Department of Internal Medicine, Keiyu Hospital, Kanagawa, Japan.
  • Shiomi T; Department of Internal Medicine, Keiyu Hospital, Kanagawa, Japan.
  • Ohgino K; Division of Pulmonary Medicine, Kawasaki Municipal Hospital, Kanagawa, Japan.
  • Sayama K; Division of Pulmonary Medicine, Kawasaki Municipal Hospital, Kanagawa, Japan.
  • Otsuka K; Department of Internal Medicine, Nihon Koukan Hospital, Kanagawa, Japan.
  • Miyao N; Department of Internal Medicine, Nihon Koukan Hospital, Kanagawa, Japan.
  • Odani T; Department of Rheumatology, National Hospital Organization Hokkaido Medical Center, Hokkaido, Japan.
  • Oyamada Y; Department of Respiratory Medicine, National Hospital Organisation Tokyo Medical Center, Tokyo, Japan.
  • Masuzawa K; Department of Respiratory Medicine, Kitasato University Kitasato Institute Hospital, Tokyo, Japan.
  • Nakayama S; Department of Respiratory Medicine, Kitasato University Kitasato Institute Hospital, Tokyo, Japan.
  • Suzuki Y; Department of Respiratory Medicine, Kitasato University Kitasato Institute Hospital, Tokyo, Japan.
  • Baba R; Pulmonary Division, Department Internal Medicine, Saiseikai Utsunomiya Hospital, Tochigi, Japan.
  • Nakachi I; Pulmonary Division, Department Internal Medicine, Saiseikai Utsunomiya Hospital, Tochigi, Japan.
  • Kuwahara N; Department of Medicine, Division of Allergology and Respiratory Medicine, Showa University Koto Toyosu Hospital, Tokyo, Japan.
  • Ishiguro T; Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Saitama, Japan.
  • Mashimo S; Department of Respiratory Medicine, Toyohashi Municipal Hospital, Aichi, Japan.
  • Minematsu N; Department of Internal Medicine, Hino Municipal Hospital, Tokyo, Japan.
  • Ueda S; Department of Internal Medicine, Saitama Medical Center, Saitama, Japan.
  • Manabe T; Division of Pulmonary Medicine, Department of Internal Medicine, Tachikawa Hospital, Tokyo, Japan.
  • Funatsu Y; Division of Pulmonary Medicine, Department of Internal Medicine, Tachikawa Hospital, Tokyo, Japan.
  • Koh H; Division of Pulmonary Medicine, Department of Internal Medicine, Tachikawa Hospital, Tokyo, Japan.
BMJ Open Respir Res ; 8(1)2021 11.
Article in English | MEDLINE | ID: covidwho-1537963
ABSTRACT

INTRODUCTION:

The rapid spread of COVID-19 posed a global burden. Substantial number of people died of the disease in the acute phase of infection. In addition, a significant proportion of patients have been reported to suffer from post-acute phase symptoms, sequelae of COVID-19, which may negatively influence the quality of daily living and/or socioeconomic circumstances of the patients. However, no previous study has comprehensively and objectively assessed the quality of life of patients by using existing international scales. Further, evidence of socioeconomic consequences among patients with COVID-19 is scarce. To address the multidimensional issues from sequelae of COVID-19, evidence from comprehensive surveys beyond clinical perspectives is critical that investigates health, and social determinants of disease progression as well as socioeconomic consequences at a large scale. METHODS AND

ANALYSIS:

In this study, we plan to conduct a nationwide and comprehensive survey for the sequelae of COVID-19 in a total of 1000 patients diagnosed at 27 hospitals throughout Japan. This study will evaluate not only the health-related status of patients from clinical perspectives but also the Health-related Quality of Life (HRQoL) scores, socioeconomic status and consequences to discuss the sequelae of the disease and the related risk factors. The primary endpoint is the frequency of long-term complications of COVID-19 infection. The secondary endpoints are risk factors for progression to sequelae of COVID-19 infection. The study will provide robust and important evidence as a resource to tackle the issues from the sequelae of COVID-19 from the multi-dimensional perspectives. ETHICS AND DISSEMINATION This trial was approved by the Keio University School of Medicine Ethics Committee (20200243, UMIN000042299). The results of this study will be reported at a society meeting or published in a peer-reviewed journal.
Subject(s)
Keywords
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Humans Country/Region as subject: Asia Language: English Year: 2021 Document Type: Article Affiliation country: Bmjresp-2021-001015

Similar

MEDLINE
LILACS
LIS
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Humans Country/Region as subject: Asia Language: English Year: 2021 Document Type: Article Affiliation country: Bmjresp-2021-001015