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Public screening for COVID-19 in Wuhan, China and beware of the antibody positive in women and tumor patients.
Shang, Yufeng; Liang, Yuxing; Liu, Tao; Li, Jingfeng; Zhou, Fuling.
  • Shang Y; Department of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Liang Y; Department of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Liu T; Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Li J; Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Zhou F; Department of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, China.
J Med Virol ; 94(4): 1535-1539, 2022 04.
Article in English | MEDLINE | ID: covidwho-1540138
ABSTRACT
The novel coronavirus disease 2019 (COVID-19) has become a global health emergency. Early detection and intervention are key factors for improving outcomes in patients with COVID-19. Real-time reverse transcriptase polymerase chain reaction-based molecular assays and antibody for detecting SARS-CoV-2 in respiratory specimens are the current reference standard for COVID-19 diagnosis. Clinical implications of different specimen types for nucleic acid and antibody testing of COVID-19 in Zhongnan hospital of Wuhan University were analyzed. Compared with health groups, tumor patients had higher rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (+/-) immunoglobulin M (IgM) (+) immunoglobulin G (IgG) (+). The rate of SARS-CoV-2 (-) IgM (+) IgG (-) or SARS-CoV-2 (-) IgM (-) IgG (+) in female was significantly higher than that in male. These results can help governments to take screening measures to prevent the COVID-19 pandemic again.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 / Antibodies, Viral / Neoplasms Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Country/Region as subject: Asia Language: English Journal: J Med Virol Year: 2022 Document Type: Article Affiliation country: Jmv.27483

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 / Antibodies, Viral / Neoplasms Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Country/Region as subject: Asia Language: English Journal: J Med Virol Year: 2022 Document Type: Article Affiliation country: Jmv.27483