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Differences in the case fatality risks associated with SARS-CoV-2 Delta and non-Delta variants in relation to vaccine coverage: An early ecological study in the United Kingdom.
Zhao, Shi; Lou, Jingzhi; Cao, Lirong; Chong, Ka Chun; Zee, Benny C Y; Chan, Paul K S; Wang, Maggie H.
  • Zhao S; JC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China; CUHK Shenzhen Research Institute, Shenzhen, China.
  • Lou J; JC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China.
  • Cao L; JC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China; CUHK Shenzhen Research Institute, Shenzhen, China. Electronic address: caolr@link.cuhk.edu.hk.
  • Chong KC; JC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China; CUHK Shenzhen Research Institute, Shenzhen, China. Electronic address: marc@cuhk.edu.hk.
  • Zee BCY; JC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China; CUHK Shenzhen Research Institute, Shenzhen, China. Electronic address: bzee@cuhk.edu.hk.
  • Chan PKS; Department of Microbiology, Chinese University of Hong Kong, Hong Kong, China. Electronic address: paulkschan@cuhk.edu.hk.
  • Wang MH; JC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China; CUHK Shenzhen Research Institute, Shenzhen, China. Electronic address: maggiew@cuhk.edu.hk.
Infect Genet Evol ; 97: 105162, 2022 01.
Article in English | MEDLINE | ID: covidwho-1540856
ABSTRACT
The circulation of SARS-CoV-2 Delta (i.e., B.1.617.2) variants challenges the pandemic control. Our analysis showed that in the United Kingdom (UK), the reported case fatality ratio (CFR) decreased from May to July 2021 for non-Delta variant, whereas the decreasing trends of the CFR of Delta variant appeared weak and insignificant. The association between vaccine coverage and CFR might be stratified by different circulating variants. Due to the limitation of ecological study design, the interpretation of our results should be treated with caution.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccination Coverage / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Type of study: Observational study / Prognostic study Topics: Vaccines / Variants Limits: Humans Country/Region as subject: Europa Language: English Journal: Infect Genet Evol Journal subject: Biology / Communicable Diseases / Genetics Year: 2022 Document Type: Article Affiliation country: J.meegid.2021.105162

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccination Coverage / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Type of study: Observational study / Prognostic study Topics: Vaccines / Variants Limits: Humans Country/Region as subject: Europa Language: English Journal: Infect Genet Evol Journal subject: Biology / Communicable Diseases / Genetics Year: 2022 Document Type: Article Affiliation country: J.meegid.2021.105162