[Senolytics against Covid-19?] / Les sénolytiques contre la Covid-19 ? - Chroniques génomiques.

ABSTRACT

The elimination of some senescent cells by « senolytic ¼ compounds can greatly improve the health of aged mice and in some cases reverse the effects of aging. Using a microbial exposure system that closely models coronavirus infection, it is possible to largely protect old mice from the effects of viral infection. This immediately suggests clinical application of the approach, and is the aim of ongoing phase II clinical trials in Covid-19 patients.