COVID-19, circadian rhythms and sleep: from virology to chronobiology.
Interface Focus
; 11(6): 20210043, 2021 Dec 06.
Article
in English
| MEDLINE | ID: covidwho-1546115
ABSTRACT
Various aspects of our physiology and immune response to pathogens are under 24 h circadian control and its role in clinical and research practice is becoming increasingly recognized. Severe acute respiratory syndrome coronavirus-2, the causative agent of Coronavirus disease 2019 (COVID-19) has affected millions of people to date. Cross-disciplinary approaches and collaborative efforts have led to an unprecedented speed in developing novel therapies and vaccines to tackle the COVID-19 pandemic. Circadian misalignment and sleep disruption have a profound impact on immune function and subsequently on the ability of individuals to combat infections. This review summarizes the evidence on the interplay between circadian biology, sleep and COVID-19 with the aim to identify areas of translational potentials that may inform diagnostic and therapeutic strategies in this pandemic.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Prognostic study
/
Randomized controlled trials
Topics:
Vaccines
Language:
English
Journal:
Interface Focus
Year:
2021
Document Type:
Article
Affiliation country:
Rsfs.2021.0043
Similar
MEDLINE
...
LILACS
LIS